LOCUS       AJF01493.1               506 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative aldehyde
            dehydrogenase (NAD+) dependent protein.
ACCESSION   CP007027-149
PROTEIN_ID  AJF01493.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /locus_tag="Y980_0147"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00070"
                     /inference="protein motif:PROSITE:PS00687"
                     /note="Rv0147, (MTCI5.21) Probable aldehyde dehydrogenase
                     (NAD+) dependent, similar to others e.g. DHAP_RAT|P11883
                     aldehyde dehydrogenase (dimeric NADP-preferring) (452 aa).
                     Also similar to several Mycobacterium tuberculosis
                     aldehyde dehydrogenases e.g. Rv0768, Rv2858c, etc.
                     Contains PS00687 aldehyde dehydrogenases glutamic acid
                     active site, and PS00070 aldehyde dehydrogenases cysteine
                     active site. Belongs to the aldehyde dehydrogenases
                     family."
                     /transl_table=11
                     /db_xref="GOA:L0T5P6"
                     /db_xref="InterPro:IPR012394"
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016160"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="UniProtKB/TrEMBL:L0T5P6"
BEGIN
        1 MSDRVKAVAP PDGRTMMTTE SVARKTQKSE TEAPREPAPV SDEKQTDVAK TVARLRKTFA
       61 SGRTRSVEWR KQQLRALQKL MDENEDAIAA ALAEDLDRNP FEAYLADIAT TSAEAKYAAK
      121 RVRRWMRRRY LLLEVPQLPG RGWVEYEPYG TVLIIGAWNY PFYLTLGPAV GAIAAGNAVV
      181 LKPSEIAAAS AHLMTELVYR YLDTEAIAVV QGDGAVSQEL IAQGFDRVMF TGGTEIGRKV
      241 YEGAAPHLTP VTLELGGKSP VIVAADADVD VAAKRIAWIK LLNAGQTCVA PDYVLADATV
      301 RDELVSKITA ALTKFRSGAP QGMRIVNQRQ FDRLSGYLAA AKTDAAADGG GVVVGGDCDA
      361 SNLRIQPTVV VDPDPDGPLM SNEIFGPILP VVTVKSLDDA IRFVNSRPKP LSAYLFTKSR
      421 AVRERVIREV PAGGMMVNHL AFQVSTAKLP FGGVGASGMG AYHGRWGFEE FSHRKSVLTK
      481 PTRPDLSSFI YPPYTERAIK VARRLF
//