LOCUS       AJF01490.1               280 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative transcriptional
            regulatory protein (possibly TetR-family) protein.
ACCESSION   CP007027-146
PROTEIN_ID  AJF01490.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /locus_tag="Y980_0144"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0144, (MTCI5.18) Probable transcriptional
                     regulator, possibly TetR family. Has region similar to
                     others e.g. Q59431|UIDR_ECOLI|GUSR|B1618|Z2623|ECS2326 UID
                     operon repressor (GUS operon) from Escherichia coli
                     strains K12 and O157:H7 (196 aa). Contains probable
                     helix-turn helix motif from aa 109-130 (Score 1463, +4.17
                     SD). Could belong to the TetR/AcrR family of
                     transcriptional regulators."
                     /transl_table=11
                     /db_xref="GOA:L7N5S4"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N5S4"
BEGIN
        1 MPHSWTPTSV MTPPLVVAAF RPVGHYRLAT DRAGGPCSPP ATGAKLTSSV ASRPTVGTKP
       61 QWWHTLVMSM SLTAGRGPGR PPAAKADETR KRILHAARQV FSERGYDGAT FQEIAVRADL
      121 TRPAINHYFA NKRVLYQEVV EQTHELVIVA GIERARREPT LMGRLAVVVD FAMEADAQYP
      181 ASTAFLATTV LESQRHPELS RTENDAVRAT REFLVWAVND AIERGELAAD VDVSSLAETL
      241 LVVLCGVGFY IGFVGSYQRM ATITDSFQQL LAGTLWRPPT
//