LOCUS       AJF01362.1               514 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Phosphoserine/threonine
            phosphatase PstP protein.
ACCESSION   CP007027-18
PROTEIN_ID  AJF01362.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="pstP"
                     /locus_tag="Y980_0018c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0018c, (MTCY10H4.18c)
                     PstP,phosphoserine/threonine phosphatase. Experimental
                     studies have shown that PstP specifically dephosporylates
                     model phospho-Ser/Thr substrates and it is likely that
                     PknB (Rv0014c) and PstP may act as a functional pair in
                     vivo to control mycobacterial cell growth (See Boitel et
                     al.,2003)."
                     /transl_table=11
                     /db_xref="GOA:P71588"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR015655"
                     /db_xref="PDB:1TXO"
                     /db_xref="PDB:2CM1"
                     /db_xref="UniProtKB/Swiss-Prot:P71588"
BEGIN
        1 MARVTLVLRY AARSDRGLVR ANNEDSVYAG ARLLALADGM GGHAAGEVAS QLVIAALAHL
       61 DDDEPGGDLL AKLDAAVRAG NSAIAAQVEM EPDLEGMGTT LTAILFAGNR LGLVHIGDSR
      121 GYLLRDGELT QITKDDTFVQ TLVDEGRITP EEAHSHPQRS LIMRALTGHE VEPTLTMREA
      181 RAGDRYLLCS DGLSDPVSDE TILEALQIPE VAESAHRLIE LALRGGGPDN VTVVVADVVD
      241 YDYGQTQPIL AGAVSGDDDQ LTLPNTAAGR ASAISQRKEI VKRVPPQADT FSRPRWSGRR
      301 LAFVVALVTV LMTAGLLIGR AIIRSNYYVA DYAGSVSIMR GIQGSLLGMS LHQPYLMGCL
      361 SPRNELSQIS YGQSGGPLDC HLMKLEDLRP PERAQVRAGL PAGTLDDAIG QLRELAANSL
      421 LPPCPAPRAT SPPGRPAPPT TSETTEPNVT SSPASPSPTT SAPAPTGTTP AIPTSASPAA
      481 PASPPTPWPV TSSPTMAALP PPPPQPGIDC RAAA
//