LOCUS ACS93392.1 570 aa PRT VRL 09-MAY-2013 DEFINITION Human betaherpesvirus 5 protein UL49 protein. ACCESSION GQ221974-55 PROTEIN_ID ACS93392.1 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235154) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235154) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235154) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235154) AUTHORS Griffin,C., Wang,E.C., McSharry,B.P., Rickards,C., Browne,H., Wilkinson,G.W. and Tomasec,P. TITLE Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18 JOURNAL J. Gen. Virol. 86 (PT 11), 2999-3008 (2005) PUBMED 16227221 REFERENCE 5 (bases 1 to 235154) AUTHORS Cunningham,C., Gatherer,D., Hilfrich,B., Baluchova,K., Dargan,D.J., Thomson,M., Griffiths,P.D., Wilkinson,G.W., Schulz,T.F. and Davison,A.J. TITLE Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens JOURNAL J. Gen. Virol. 91 (PT 3), 605-615 (2010) PUBMED 19906940 REFERENCE 6 (bases 1 to 235154) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (28-MAY-2009) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK COMMENT On or before Aug 17, 2009 this sequence version replaced AY446863.1, AY446867.1, AY446875.1, AY169795.2, AY156040.1, AY325311.1, DQ195526.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="3157" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="United Kingdom" /collection_date="2001" /note="sequenced at passage 3 in human fibroblasts; three genes are mutated (RL13, UL40 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="UL49" BEGIN 1 MGNRRLRHAP HTATDEFHQA LRRLFAPLCV HEDHFHVQLV IGRGALQPEE AAVETSQPPA 61 QFAAQTSAVL QQQLVHHVPR SCVLHLFVTD KRFLNRELGD RLYQRFLREW LVCRQAEREA 121 VTALFQRMVM TKPYFVFLAY VYSMDCLHTV AVRTMAFLRF ERYDTDYLLR RLRLYPPERL 181 HALLDGVTAS LLGDLHRFLF GVDLRLPVLH PTSSPCLALL RAKRFDARAD LAVYHRNQWC 241 HQRQPRSPQL RGLIAALRRH AGKVPCGNPL YVLARQAVQT FCDTCPRYLV PLRALGLHDE 301 TRGGGSTAAA AAVGHAGAGQ QARHVEPTKI VLFALSAALR GGLIGSVIDL PLWCLCRLKC 361 ERHLDARSLV AVVCRQCGHC LNLGKEKLHC QQNFPLNSMF YYRDRQEKSV IFNTHAELVH 421 CSLCGSQRVV RQRVYELVSE TLFGQRCVRV GWKAVLGLNA ACAVYDHRLA FDVILPCAAR 481 TCDSTVVVRG VTVPRLLRLT SHGHGLLCAR CQTGEYRDSC LESEDGAPLC RGCALVKQTA 541 CHVGGHIVQQ ARGGLAATSS SSSPHGLPHV //