LOCUS       ACM55986.1               213 aa    PRT              BCT 01-MAR-2021
DEFINITION  Halorubrum lacusprofundi ATCC 49239 beta-lactamase domain
            protein protein.
ACCESSION   CP001365-380
PROTEIN_ID  ACM55986.1
SOURCE      Halorubrum lacusprofundi ATCC 49239
  ORGANISM  Halorubrum lacusprofundi ATCC 49239
            Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria;
            Haloferacales; Haloferacaceae; Halorubrum.
REFERENCE   1  (bases 1 to 2735295)
  AUTHORS   Dassarma,S., Capes,M.D., Karan,R. and Dassarma,P.
  TITLE     Amino acid substitutions in cold-adapted proteins from Halorubrum
            lacusprofundi, an extremely halophilic microbe from antarctica
  JOURNAL   PLoS One 8 (3), e58587 (2013)
   PUBMED   23536799
REFERENCE   2  (bases 1 to 2735295)
  AUTHORS   Karan,R., Capes,M.D., DasSarma,P. and DasSarma,S.
  TITLE     Cloning, overexpression, purification, and characterization of a
            polyextremophilic beta-galactosidase from the Antarctic
            haloarchaeon Halorubrum lacusprofundi
  JOURNAL   BMC Biotechnol 13, 3 (2013)
   PUBMED   23320757
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2735295)
  AUTHORS   Anderson,I.J., DasSarma,P., Lucas,S., Copeland,A., Lapidus,A., Del
            Rio,T.G., Tice,H., Dalin,E., Bruce,D.C., Goodwin,L., Pitluck,S.,
            Sims,D., Brettin,T.S., Detter,J.C., Han,C.S., Larimer,F.,
            Hauser,L., Land,M., Ivanova,N., Richardson,P., Cavicchioli,R.,
            DasSarma,S., Woese,C.R. and Kyrpides,N.C.
  TITLE     Complete genome sequence of the Antarctic Halorubrum lacusprofundi
            type strain ACAM 34
  JOURNAL   Stand Genomic Sci 11 (1), 70 (2016)
   PUBMED   27617060
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2735295)
  AUTHORS   Laye,V.J., Karan,R., Kim,J.M., Pecher,W.T., DasSarma,P. and
            DasSarma,S.
  TITLE     Key amino acid residues conferring enhanced enzyme activity at cold
            temperatures in an Antarctic polyextremophilic beta-galactosidase
  JOURNAL   Proc Natl Acad Sci U S A 114 (47), 12530-12535 (2017)
   PUBMED   29109294
REFERENCE   5  (bases 1 to 2735295)
  AUTHORS   Laye,V.J. and DasSarma,S.
  TITLE     An Antarctic Extreme Halophile and Its Polyextremophilic Enzyme:
            Effects of Perchlorate Salts
  JOURNAL   Astrobiology 18 (4), 412-418 (2018)
   PUBMED   29189043
REFERENCE   6  (bases 1 to 2735295)
  AUTHORS   DasSarma,S., DasSarma,P., Laye,V.J. and Schwieterman,E.W.
  TITLE     Extremophilic models for astrobiology: haloarchaeal survival
            strategies and pigments for remote sensing
  JOURNAL   Extremophiles 24 (1), 31-41 (2020)
   PUBMED   31463573
REFERENCE   7  (bases 1 to 2735295)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Sims,D., Brettin,T.,
            Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Ivanova,N., Anderson,I., DasSarma,S., Cavicchioli,R. and
            Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2009) US DOE Joint Genome Institute, 2800
            Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     URL -- http://www.jgi.doe.gov
            JGI Project ID: 4001421
            Source DNA available from Professor Shiladitya DasSarma
            Archaea available from ATCC: ATCC 49239
            Contacts: Ricardo Cavicchioli (r.cavicchioli@unsw.edu.au)
                      Shiladitya DasSarma (sdassarma@som.umaryland.edu)
                      David Bruce (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
FEATURES             Qualifiers
     source          /organism="Halorubrum lacusprofundi ATCC 49239"
                     /mol_type="genomic DNA"
                     /strain="ATCC 49239"
                     /culture_collection="ATCC:49239"
                     /type_material="type strain of Halorubrum lacusprofundi"
                     /db_xref="taxon:416348"
                     /chromosome="1"
     protein         /locus_tag="Hlac_0383"
                     /inference="protein motif:PFAM:PF00753"
                     /note="PFAM: beta-lactamase domain protein; KEGG:
                     hwa:HQ1377A hydrolase (hydroxyacylglutathione hydrolase)"
                     /transl_table=11
                     /db_xref="InterPro:IPR001279"
BEGIN
        1 MEPITVTADA EEFTCNAYLV SGEAPTLVDA GTMPGVDDVI ADALDEAGVD GLDRVVLTHQ
       61 HHDHVGQLDA VLDRFDATLY ANAAHPRRDV AIGDGDEILV GDEPCEVVET PGHAADHISL
      121 VGDDRVYSGD VVVYNDGAFD DGSFGRTDMA GQSREVLIES LHTLLDRLPD TASAMYPGHG
      181 DVYRASDGPD TVREVIERAT ERAERREPKY PDE
//