LOCUS       ABR24161.1               131 aa    PRT              HUM 05-MAY-2008
DEFINITION  Homo sapiens virus-induced signaling adaptor variant 1a protein.
ACCESSION   EF467323-1
PROTEIN_ID  ABR24161.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Lad,S.P., Yang,G., Scott,D.A., Chao,T.H., Correia Jda,S., de la
            Torre,J.C. and Li,E.
  TITLE     Identification of MAVS splicing variants that interfere with
            RIGI/MAVS pathway signaling
  JOURNAL   Mol. Immunol. 45 (8), 2277-2287 (2008)
   PUBMED   18207245
REFERENCE   2  (bases 1 to 1448)
  AUTHORS   Lad,S., Yang,G., Correia,J.D.S., Mathison,J. and Li,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-2007) Immunology, The Scripps Research Institute,
            10550 North Torrey Pines Road, La Jolla, CA 92037, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000468802"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /PCR_primers="fwd_seq: ggatccatgccgtttgctgaagacaag,
                     rev_seq: aagcttctagtgcagacgccgcc"
     protein         /gene="VISA"
                     /note="VISA1a; exon 2 deletion induces frameshift; CARD
                     domain; inhibition of wt VISA induced NF-kB and IRF3
                     activation; alternatively spliced"
BEGIN
        1 MPFAEDKTYK YICRNFSNFC NVDVVEILPY LPCLTARDQG PRTVPQTHWS HRHFLLRGQG
       61 PPHLLRPTAS PTTAAERRSQ VTPCLSRRPR RQSPQERIQS KPCRRSAPEP SQGIQMVAPW
      121 SPPLTWQPSA L
//