LOCUS       AAV30551.1               971 aa    PRT              HUM 20-OCT-2004
DEFINITION  Homo sapiens alcadein alpha-1 protein.
ACCESSION   AY753301-1
PROTEIN_ID  AAV30551.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2916)
  AUTHORS   Araki,Y., Tomita,S., Yamaguchi,H., Miyagi,N., Sumioka,A., Kirino,Y.
            and Suzuki,T.
  TITLE     Novel cadherin-related membrane proteins, Alcadeins, enhance the
            X11-like protein-mediated stabilization of amyloid beta-protein
            precursor metabolism
  JOURNAL   J. Biol. Chem. 278 (49), 49448-49458 (2003)
   PUBMED   12972431
REFERENCE   2  (bases 1 to 2916)
  AUTHORS   Araki,Y., Miyagi,N., Kato,N., Yoshida,T., Wada,S., Nishimura,M.,
            Komano,H., Yamamoto,T., De Strooper,B., Yamamoto,K. and Suzuki,T.
  TITLE     Coordinated metabolism of Alcadein and amyloid beta-protein
            precursor regulates FE65-dependent gene transactivation
  JOURNAL   J. Biol. Chem. 279 (23), 24343-24354 (2004)
   PUBMED   15037614
REFERENCE   3  (bases 1 to 2916)
  AUTHORS   Araki,Y. and Suzuki,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-SEP-2004) Dept. of Neurosci., Grad. Sch. of Pharm.
            Sci., Hokkaido University, Kita-12 Nishi-6, Kita-ku, Sapporo,
            Hokkaido 060-0812, Japan
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000257619"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /cell_line="SHSY5Y"
                     /cell_type="neuroblastoma cells"
BEGIN
        1 MLRRPAPALA PAARLLLAGL LCGGGVWAAR VNKHKPWLEP TYHGIVTEND NTVLLDPPLI
       61 ALDKDAPLRF AGEICGFKIH GQNVPFDAVV VDKSTGEGVI RSKEKLDCEL QKDYSFTIQA
      121 YDCGKGPDGT NVKKSHKATV HIQVNDVNEY APVFKEKSYK ATVIEGKQYD SILRVEAVDA
      181 DCSPQFSQIC SYEIITPDVP FTVDKDGYIK NTEKLNYGKE HQYKLTVTAY DCGKKRATED
      241 VLVKISIKPT CTPGWQGWNN RIEYEPGTGA LAVFPNIHLE TCDEPVASVQ ATVELETSHI
      301 GKGCDRDTYS EKSLHRLCGA AAGTAELLPS PSGSLNWTMG LPTDNGHDSD QVFEFNGTQA
      361 VRIPDGVVSV SPKEPFTISV WMRHGPFGRK KETILCSSDK TDMNRHHYSL YVHGCRLIFL
      421 FRQDPSEEKK YRPAEFHWKL NQVCDEEWHH YVLNVEFPSV TLYVDGTSHE PFSVTEDYPL
      481 HPSKIETQLV VGACWQEFSG VENDNETEPV TVASAGGDLH MTQFFRGNLA GLTLRSGKLA
      541 DKKVIDCLYT CKEGLDLQVL EDSGRGVQIQ AHPSQLVLTL EGEDLGELDK AMQHISYLNS
      601 RQFPTPGIRR LKITSTIKCF NEATCISVPP VDGYVMVLQP EEPKISLSGV HHFARAASEF
      661 ESSEGVFLFP ELRIISTITR EVEPEGDGAE DPTVQESLVS EEIVHDLDTC EVTVEGEELN
      721 HEQESLEVDM ARLQQKGIEV SSSELGMTFT GVDTMASYEE VLHLLRYRNW HARSLLDRKF
      781 KLICSELNGR YISNEFKVEV NVIHTANPME HANHMAAQPQ FVHPEHRSFV DLSGHNLANP
      841 HPFAVVPSTA TVVIVVCVSF LVFMIILGVF RIRAAHRRTM RDQDTGKENE MDWDDSALTI
      901 TVNPMETYED QHSSEEEEEE EEEEESEDGE EEDDITSAES ESSEEEEGEQ GDPQNATRQQ
      961 QLEWDDSTLS Y
//