LOCUS AAR31539.2 683 aa PRT VRL 09-MAY-2013 DEFINITION Human betaherpesvirus 5 protein UL112 protein. ACCESSION GQ221974-101 PROTEIN_ID AAR31539.2 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235154) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235154) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235154) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235154) AUTHORS Griffin,C., Wang,E.C., McSharry,B.P., Rickards,C., Browne,H., Wilkinson,G.W. and Tomasec,P. TITLE Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18 JOURNAL J. Gen. Virol. 86 (PT 11), 2999-3008 (2005) PUBMED 16227221 REFERENCE 5 (bases 1 to 235154) AUTHORS Cunningham,C., Gatherer,D., Hilfrich,B., Baluchova,K., Dargan,D.J., Thomson,M., Griffiths,P.D., Wilkinson,G.W., Schulz,T.F. and Davison,A.J. TITLE Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens JOURNAL J. Gen. Virol. 91 (PT 3), 605-615 (2010) PUBMED 19906940 REFERENCE 6 (bases 1 to 235154) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (28-MAY-2009) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK COMMENT On or before Aug 17, 2009 this sequence version replaced AY446863.1, AY446867.1, AY446875.1, AY169795.2, AY156040.1, AY325311.1, DQ195526.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="3157" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="United Kingdom" /collection_date="2001" /note="sequenced at passage 3 in human fibroblasts; three genes are mutated (RL13, UL40 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="UL112" /note="involved in gene regulation; involved in DNA replication" intron_pos 253:1 (1/1) BEGIN 1 MDLPTTVVRK YWTFANPNRI LHQSVNQTFD VRQFVFDTAR LVNCVDGDGK VLHLNKGWLC 61 ATIMQHGEAS AGAKTQQGFM SIDITGDGEL QEHLFVRGGI VFNKSVSSVV GSSGPNESAL 121 LTMISENGNL QVTYVRHYLK NHGESSGGGG GCGAASTASA VCVSSLGGSG GTRDGPSAEE 181 QQRRRQEQRH EERRKKSSSS AGGGGGGGAG GGGGGGGSGG QHSSDSANGL LRDPRLMNRQ 241 KERRPPPSSE NDGSPPLREA KRQKTTAQHE GHGGGGKNET EQQSGGAGGG GGGGSGRMSL 301 PLDTSEAVAF LNYSSSSSAV SSSSNNHHHH HHHHNAVTDV AAGTDGALLL PIERGAVVSS 361 PSSPSSLLSL PRPSSAHSAG ETVQESEAAA TAAAAGLMMM RRMRRAPAEA AEAPPQSEEE 421 NDSTTPVSNC RVPPNSQESA APQPPRSPRF DDIIQSLTKM LNDCKEKRLC DLPLVSSRLL 481 PETSGGTVVV NHSSVARTAA AVSTAGVGPP AAACPPLVTT GVVPSGSVAG VAPVAAAVET 541 PAAPPRPVCE IKPYVVNPVV ATAAAASNSS SSSSAPLPPP PPPPPGGRRG RARNNTRGGG 601 GGGGGRNSRR QAASSSSSSS RRSRRRNNRH EDEEDNDPLL RLSQVAGSGR RRGPSFLEDG 661 LEIIDPSEEA AIAAASIAAF FDD //