LOCUS       AAR13072.1               759 aa    PRT              HUM 10-NOV-2003
DEFINITION  Homo sapiens cullin 4A protein.
ACCESSION   AY365124-1
PROTEIN_ID  AAR13072.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Higa,L.A., Mihaylov,I.S., Banks,D.P., Zheng,J. and Zhang,H.
  TITLE     Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN
            complexes constitutes a new checkpoint
  JOURNAL   Nat. Cell Biol. 5 (11), 1008-1015 (2003)
   PUBMED   14578910
  REMARK    Erratum:[Nat Cell Biol. 2003 Dec;5(12):1122]
REFERENCE   2  (bases 1 to 2280)
  AUTHORS   Higa,L.A., Mihaylov,I.S., Banks,D.P., Zheng,J. and Zhang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2003) Genetics, Yale University School of
            Medicine, 333 Cedar Street, New Haven, CT 06520, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000253220"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     protein         /gene="CUL4A"
                     /note="ubiquitin E3 ligase"
BEGIN
        1 MADEAPRKGS FSALVGRTNG LTKPAALAAA PAKPGGAGGS KKLVIKNFRD RPRLPDNYTQ
       61 DTWRKLHEAV RAVQSSTSIR YNLEELYQAV ENLCSHKVSP MLYKQLRQAC EDHVQAQILP
      121 FREDSLDSVL FLKKINTCWQ DHCRQMIMIR SIFLFLDRTY VLQNSTLPSI WDMGLELFRT
      181 HIISDKMVQS KTIDGILLLI ERERSGEAVD RSLLRSLLGM LSDLQVYKDS FELKFLEETN
      241 CLYAAEGQRL MQEREVPEYL NHVSKRLEEE GDRVITYLDH STQKPLIACV EKQLLGEHLT
      301 AILQKGLDHL LDENRVPDLA QMYQLFSRVR GGQQALLQHW SEYIKTFGTA IVINPEKDKD
      361 MVQDLLDFKD KVDHVIEVCF QKNERFVNLM KESFETFINK RPNKPAELIA KHVDSKLRAG
      421 NKEATDEELE RTLDKIMILF RFIHGKDVFE AFYKKDLAKR LLVGKSASVD AEKSMLSKLK
      481 HECGAAFTSK LEGMFKDMEL SKDIMVHFKQ HMQNQSDSGP IDLTVNILTM GYWPTYTPME
      541 VHLTPEMIKL QEVFKAFYLG KHSGRKLQWQ TTLGHAVLKA EFKEGKKEFQ VSLFQTLVLL
      601 MFNEGDGFSF EEIKMATGIE DSELRRTLQS LACGKARVLI KSPKGKEVED GDKFIFNGEF
      661 KHKLFRIKIN QIQMKETVEE QVSTTERVFQ DRQYQIDAAI VRIMKMRKTL GHNLLVSELY
      721 NQLKFPVKPG DLKKRIESLI DRDYMERDKD NPNQYHYVA
//