LOCUS       AAN86126.1               196 aa    PRT              HUM 18-APR-2006
DEFINITION  Homo sapiens interferon-lambda2 protein.
ACCESSION   AY184373-1
PROTEIN_ID  AAN86126.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Kotenko,S.V., Gallagher,G., Baurin,V.V., Lewis-Antes,A., Shen,M.,
            Shah,N.K., Langer,J.A., Sheikh,F., Dickensheets,H. and
            Donnelly,R.P.
  TITLE     IFN-lambdas mediate antiviral protection through a distinct class
            II cytokine receptor complex
  JOURNAL   Nat. Immunol. 4 (1), 69-77 (2003)
   PUBMED   12483210
REFERENCE   2  (bases 1 to 591)
  AUTHORS   Lasfar,A., Lewis-Antes,A., Smirnov,S.V., Anantha,S., Abushahba,W.,
            Tian,B., Reuhl,K., Dickensheets,H., Sheikh,F., Donnelly,R.P.,
            Raveche,E. and Kotenko,S.V.
  TITLE     Characterization of the mouse IFN-lambda ligand-receptor system:
            IFN-lambdas exhibit antitumor activity against B16 melanoma
  JOURNAL   Cancer Res. 66 (8), 4468-4477 (2006)
   PUBMED   16618774
REFERENCE   3  (bases 1 to 591)
  AUTHORS   Kotenko,S.V. and Gallagher,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-2002) Biochemistry & Molecular Biology,
            University of Medicine and Dentistry of New Jersey, New Jersey
            Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000085073"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.13"
     protein         /function="mediates antiviral protection through a unique
                     class II cytokine receptor complex composed of CRF2-12
                     (IFN-lambdaR1) and CRF2-4 (IL-10R2) subunits"
                     /note="IFN-lambda2; cytokine"
BEGIN
        1 MTGDCTPVLV LMAAVLTVTG AVPVARLHGA LPDARGCHIA QFKSLSPQEL QAFKRAKDAL
       61 EESLLLKDCR CHSRLFPRTW DLRQLQVRER PMALEAELAL TLKVLEATAD TDPALVDVLD
      121 QPLHTLHHIL SQFRACIQPQ PTAGPRARGR LHHWLYRLQE APKKESPGCL EASVTFNLFR
      181 LLTRDLNCVA SGDLCV
//