LOCUS       AAL22827.1               729 aa    PRT              BCT 24-JUL-2018
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium
            str. LT2 3-hydroxyacyl-coA dehydrogenase of 4-enzyme FadB
            protein protein.
ACCESSION   AE006468-3864
PROTEIN_ID  AAL22827.1
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4857450)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (bases 1 to 4857450)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
REFERENCE   3  (bases 1 to 4857450)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
COMMENT     On Jan 13, 2016 this sequence version replaced AE006468.1.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
FEATURES             Qualifiers
     source          2776826..2844430,2879238..4857450)
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /mol_type="genomic DNA"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     source          /organism="Salmonella phage Fels-1"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:128975"
     source          /organism="Phage Gifsy-2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:129862"
     source          /organism="Phage Gifsy-1"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:129861"
     source          /organism="Salmonella virus Fels2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:194701"
     protein         /gene="fadB"
                     /locus_tag="STM3983"
                     /EC_number="4.2.1.17"
                     /EC_number="5.1.2.3"
                     /EC_number="2.3.1.16"
                     /EC_number="1.1.1.35"
                     /note="similar to E. coli 4-enzyme protein:
                     3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA
                     epimerase; delta(3)-cis-delta(2)-trans-enoyl-CoA
                     isomerase; enoyl-CoA hydratase (AAC76849.1); Blastp hit to
                     AAC76849.1 (729 aa), 95% identity in aa 1 - 729"
                     /transl_table=11
BEGIN
        1 MLYKGDTLYL DWLEDGIAEL VFDAPGSVNK LDTATVASLG QALEVLEKQH DLKGLLLRSN
       61 KAAFIVGADI TEFLSLFLVP EEQLSQWLHF ANSVFNRLED LPVPTLAAVN GYALGGGCEC
      121 VLATDYRLAT PDLRIGLPET KLGIMPGFGG SVRLPRMLGA DSALEIIAAG KDVGAEHALK
      181 IGLVDGVVKQ EKLIEGAIAV LRQAITGDLD WRAKRQPKLE PLKLSKIEAA MSFTIAKGMV
      241 AQTAGKHYPA PMTAVKTIEA AARFGREEAL NLENKSFVPL AHTNEARALV GIFLNDQYVK
      301 GKAKKLTKDI ETPKQAAVLG AGIMGGGIAY QSAWKGVPVI MKDINDKSLN LGMTEAAKLL
      361 NKQLERGKID GLKLAGVIST IHPTLDYAGF DRVDVVVEAV VENPKVKKAV LAETEQKVRP
      421 ETVLASNTST IPIGELASAL ERPENFCGMH FFNPVHRMPL VEIIRGEKSS DETIAKVVAW
      481 ASKMGKTPIV VNDCPGFFVN RVLFPYFAGF SQLLRDGADF RKVDKVMEKQ FGWPMGPAYL
      541 LDVVGIDTAH HAQAVMAAGF PQRMQKDYRD AIDALFDASR FGQKNGLGFW RYKEDSKGKP
      601 KKEEDAAVDD LLASVSQPKR DFSDDEIIAR MMIPMINEVV RCLEEGIIAS PAEADMALVY
      661 GLGFPPFHGG AFRWLDTQGS AKYLDMAQQY QHLGPLYEVP EGLRNKARHN EPYYPPVEPA
      721 RPVGSLKTA
//