LOCUS       AAI12927.1              1306 aa    PRT              HUM 06-JUN-2006
DEFINITION  Homo sapiens ARHGEF10 protein protein.
ACCESSION   BC112926-1
PROTEIN_ID  AAI12927.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5508)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 5508)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2006) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 255 Row: p Column: 20
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 62548863.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000340504"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:131664 IMAGE:6500770"
                     /tissue_type="Uterus, leiomyosarcoma"
                     /clone_lib="NIH_MGC_71"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     protein         /gene="ARHGEF10"
                     /gene_synonym="GEF10"
                     /db_xref="GeneID:9639"
                     /db_xref="HGNC:HGNC:14103"
                     /db_xref="MIM:608136"
BEGIN
        1 MDQREPLPPA PAENEMKYDT NNNEEEEGEQ FDFDSGDEIP EADRQAPSAP ETGGAGASEA
       61 PAPTGGEDGA GAETTPVAEP TKLVLPMKVN PYSVIDITPF QEDQPPTPVP SAEEENVGLH
      121 VPCGYLVPVP CGYAVPSNLP LLLPAYSSPV IICATSLDEE AETPEVTEDR QPNSLSSEEP
      181 PTSEDQVGRE DSALARWAAD PANTAWMENP EEAIYDDVPR ENSDSEPDEM IYDDVENGDE
      241 GGNSSLEYGW SSSEFESYEE QSDSECKNGI PRSFLRSNHK KQMQKLVKAA KDGTKDGLER
      301 TRAAVKRGRS FIRTKSLIAQ DHRSSLEEEQ NFFIDVDCKH PEAILTPMPE GLSQQQVVRR
      361 YILGSVVDSE KNYVDALKRI LEQYEKPLSE MEPKVLSERK LKTVFYRVKE ILQCHSLFQI
      421 ALASRVSEWD SVEMIGDVFV ASFSKSMVLD AYSEYVNNFS TAVAVLKKTC ATKPAFLEFL
      481 KQEQEASPDR TTLYSLMMKP IQRFPQFILL LQDMLKNTSK GHPDRLPLQM ALTELETLAE
      541 KLNERKRDAD QRCEVKQIAK AINERYLNKL LSSGSRYLIR SDDMIETVYN DRGEIVKTKE
      601 RRVFMLNDVL MCATVSSRPS HDSRVMSSQR YLLKWSVPLG HVDAIEYGSS AGTGEHSRHL
      661 AVHPPESLAV VANAKPNKVY MGPGQLYQDL QNLLHDLNVI GQITQLIGNL KGNYQNLNQS
      721 VAHDWTSGLQ RLILKKEDEI RAADCCRIQL QLPGKQDKSG RPTFFTAVFN TFTPAIKESW
      781 VNSLQMAKLA LEEENHMGWF CVEDDGNHIK KEKHPLLVGH MPVMVAKQQE FKIECAAYNP
      841 EPYLNNESQP DSFSTAHGFL WIGSCTHQMG QIAIVSFQNS TPKVIECFNV ESRILCMLYV
      901 PVEEKRREPG APPDPETPAV RASDVPTICV GTEEGSISIY KSSQGSKKVR LQHFFTPEKS
      961 TVMSLACTSQ SLYAGLVNGA VASYARAPDG SWDSEPQKVI KLGVLPVRSL LMMEDTLWAA
     1021 SGGQVFIISV ETHAVEGQLE AHQEEGMVIS HMAVSGVGIW IAFTSGSTLR LFHTETLKHL
     1081 QDINIATPVH NMLPGHQRLS VTSLLVCHGL LMVGTSLGVL VALPVPRLQG IPKVTGRGMV
     1141 SYHAHNSPVK FIVLATALHE KDKDKSRDSL APGPEPQDED QKDALPSGGA GSSLSQGDPD
     1201 AAIWLGDSLG SMTQKSDLSS SSGSLSLSHG SSSLEHRSED STIYDLLKDP VSLRSKARRA
     1261 KKAKASSALV VCGGQGHRRV HRKARQPHQE ELAPTVMVWQ IPLLNI
//