LOCUS       AAH20567.1               959 aa    PRT              HUM 06-OCT-2003
DEFINITION  Homo sapiens ARHGEF2 protein protein.
ACCESSION   BC020567-1
PROTEIN_ID  AAH20567.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4125)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 4125)
  AUTHORS   Strausberg,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Cancer Genomics Office, National Cancer
            Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
            USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: David N. Louis, M.D.
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 20 Row: c Column: 24
            This clone was selected for full length sequencing because it
            passed the following selection criteria: Similarity but not
            identity to protein.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000038828"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:21557 IMAGE:4157775"
                     /tissue_type="Brain, anaplastic oligodendroglioma with
                     1p/19q loss"
                     /clone_lib="NCI_CGAP_Brn67"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     protein         /gene="ARHGEF2"
                     /gene_synonym="DKFZp547L106"
                     /gene_synonym="GEF"
                     /gene_synonym="GEF-H1"
                     /gene_synonym="GEFH1"
                     /gene_synonym="KIAA0651"
                     /gene_synonym="LFP40"
                     /gene_synonym="P40"
                     /db_xref="GeneID:9181"
                     /db_xref="MIM:607560"
BEGIN
        1 MKEAKDARYT NGHLFTTISV SGMTMCYACN KSITAKEALI CPTCNVTIHN RCKDTLANCT
       61 KVKQKQQKAA LLKNNTALQS VSLRSKTTIR ERPSSAIYPS DSFRQSLLGS RRGRSSLSLA
      121 KSVSTTNIAG HFNDESPLGL RRILSQSTDS LNMRNRTLSV ESLIDEAEVI YSELMSDFEM
      181 DEKDFAADSW SLAVDSSFLQ QHKKEVMKQQ DVIYELIQTE LHHVRTLKIM TRLFRTGMLE
      241 ELHLEPGVVQ GLFPCVDELS DIHTRFLSQL LERRRQALCP GSTRNFVIHR LGDLLISQFS
      301 GPSAEQMCKT YSEFCSRHSK ALKLYKELYA RDKRFQQFIR KVTRPAVLKR HGVQECILLV
      361 TQRITKYPLL ISRILQHSHG IEEERQDLTT ALGLVKELLS NVDEGIYQLE KGARLQEIYN
      421 RMDPRAQTPV PGKGPFGREE LLRRKLIHDG CLLWKTATGR FKDVLVLLMT DVLVFLQEKD
      481 QKYIFPTLDK PSVVSLQNLI VRDIANQEKG MFLISAAPPE MYEVHTASRD DRSTWIRVIQ
      541 QSVRTCPSRE DFPLIETEDE AYLRRIKMEL QQKDRALVEL LREKVGLFAE MTHFQAEEDG
      601 GSGMALPTLP RGLFRSESLE SPRGERLLQD AIREVEGLKD LLVGPGVELL LTPREPALPL
      661 EPDSGGNTSP GVTANGEART FNGSIELCRA DSDSSQRDRN GNQLRSPQEE ALQRLVNLYG
      721 LLHGLQAAVA QQDTLMEARF PEGPERREKL CRANSRDGEA GRAGAAPVAP EKQATELALL
      781 QRQHALLQEE LRRCRRLGEE RATEAGSLEA RLRESEQARA LLEREAEEAR RQLAALGQTE
      841 PLPAEAPWAR RPVDPRRRSL PAGDALYLSF NPPQPSRGTD RLDLPVTTRS VHRNFEDRER
      901 QELGSPEERL QDSSDPDTGS EEEGSSRLSP PHSPRDFTRM QDIPEETESR DGEAVASES
//