LOCUS       AAH06422.1               827 aa    PRT              HUM 15-JUL-2006
DEFINITION  Homo sapiens phosphofructokinase, liver protein.
ACCESSION   BC006422-1
PROTEIN_ID  AAH06422.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3385)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 3385)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: DCTD/DTP/Gazdar
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Genome Sequence Centre,
            BC Cancer Agency, Vancouver, BC, Canada
            info@bcgsc.bc.ca
            Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
            Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
            Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
            Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
            Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
            Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
            Kim MacDonald,  Mike R. Mayo, Josh Moran, Diana Palmquist, JR
            Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
            Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 18 Row: o Column: 14
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 50346003.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000032824"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:12724 IMAGE:4040291"
                     /tissue_type="Lung, large cell carcinoma"
                     /clone_lib="NIH_MGC_18"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     protein         /gene="PFKL"
                     /gene_synonym="PFK-B"
                     /db_xref="GeneID:5211"
                     /db_xref="HGNC:HGNC:8876"
                     /db_xref="MIM:171860"
BEGIN
        1 MCNQGRGRES SRGGLHVQGS CRGLSRSPQQ ETGFAKAPAG TDCFFHCSPG SRGQGDRKEE
       61 VTSEPGGTSI MSRLGGMNAA VRAVTRMGIY VGAKVFLIYE GYEGLVEGGE NIKQANWLSV
      121 SNIIQLGGTI IGSARCKAFT TREGRRAAAY NLVQHGITNL CVIGGDGSLT GANIFRSEWG
      181 SLLEELVAEG KISETTARTY SHLNIAGLVG SIDNDFCGTD MTIGTDSALH RIMEVIDAIT
      241 TTAQSHQRTF VLEVMGRHCG YLALVSALAS GADWLFIPEA PPEDGWENFM CERLGETRSR
      301 GSRLNIIIIA EGAIDRNGKP ISSSYVKDLV VQRLGFDTRV TVLGHVQRGG TPSAFDRILS
      361 SKMGMEAVMA LLEATPDTPA CVVTLSGNQS VRLPLMECVQ MTKEVQKAMD DKRFDEATQL
      421 RGGSFENNWN IYKLLAHQKP PKEKSNFSLA ILNVGAPAAG MNAAVRSAVR TGISHGHTVY
      481 VVHDGFEGLA KGQVQEVGWH DVAGWLGRGG SMLGTKRTLP KGQLESIVEN IRIYGIHALL
      541 VVGGFEAYEG VLQLVEARGR YEELCIVMCV IPATISNNVP GTDFSLGSDT AVNAAMESCD
      601 RIKQSASGTK RRVFIVETMG GYCGYLATVT GIAVGADAAY VFEDPFNIHD LKVNVEHMTE
      661 KMKTDIQRGL VLRNEKCHDY YTTEFLYNLY SSEGKGVFDC RTNVLGHLQQ GGAPTPFDRN
      721 YGTKLGVKAM LWLSEKLREV YRKGRVFANA PDSACVIGLK KKAVAFSPVT ELKKDTDFEH
      781 RMPREQWWLS LRLMLKMLAQ YRISMAAYVS GELEHVTRRT LSMDKGF
//