LOCUS       AAF91441.1               450 aa    PRT              HUM 05-DEC-2000
DEFINITION  Homo sapiens alpha 2A adrenergic receptor protein.
ACCESSION   AF281308-1
PROTEIN_ID  AAF91441.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Small,K.M., Forbes,S.L., Brown,K.M. and Liggett,S.B.
  TITLE     An asn to lys polymorphism in the third intracellular loop of the
            human alpha 2A-adrenergic receptor imparts enhanced
            agonist-promoted Gi coupling
  JOURNAL   J. Biol. Chem. 275 (49), 38518-38523 (2000)
   PUBMED   10948191
REFERENCE   2  (bases 1 to 1353)
  AUTHORS   Small,K.M., Forbes,S.L., Bridges,K.M. and Liggett,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2000) Internal Medicine, University of
            Cincinnati, 231 Bethesda Ave., Cincinnati, OH 45267, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000383898"
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     protein         /gene="ADRA2A"
                     /note="G-protein coupled receptor"
BEGIN
        1 MGSLQPDAGN ASWNGTEAPG GGARATPYSL QVTLTLVCLA GLLMLLTVFG NVLVIIAVFT
       61 SRALKAPQNL FLVSLASADI LVATLVIPFS LANEVMGYWY FGKAWCEIYL ALDVLFCTSS
      121 IVHLCAISLD RYWSITQAIE YNLKRTPRRI KAIIITVWVI SAVISFPPLI SIEKKGGGGG
      181 PQPAEPRCEI NDQKWYVISS CIGSFFAPCL IMILVYVRIY QIAKRRTRVP PSRRGPDAVA
      241 APPGGTERRP NGLGPERSAG PGGAEAEPLP TQLNGAPGEP APAGPRDTDA LDLEESSSSD
      301 HAERPPGPRR PERGPRGKGK ARASQVKPGD SLPRRGPGAT GIGTPAAGPG EERVGAAKAS
      361 RWRGRQNREK RFTFVLAVVI GVFVVCWFPF FFTYTLTAVG CSVPRTLFKF FFWFGYCNSS
      421 LNPVIYTIFN HDFRRAFKKI LCRGDRKRIV
//