LOCUS       AAD45191.1               659 aa    PRT              HUM 22-JUL-1999
DEFINITION  Homo sapiens cullin 4A protein.
ACCESSION   AF077188-1
PROTEIN_ID  AAD45191.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3643)
  AUTHORS   Chen,L.C., Manjeshwar,S., Lu,Y., Moore,D., Ljung,B.M., Kuo,W.L.,
            Dairkee,S.H., Wernick,M., Collins,C. and Smith,H.S.
  TITLE     The human homologue for the Caenorhabditis elegans cul-4 gene is
            amplified and overexpressed in primary breast cancers
  JOURNAL   Cancer Res. 58 (16), 3677-3683 (1998)
   PUBMED   9721878
REFERENCE   2  (bases 1 to 3643)
  AUTHORS   Chen,L.-C. and Smith,H.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUL-1998) Geraldine Brush Cancer Research Institute,
            CPMCRI, 2330 Clay Street, San Francisco, CA 94115, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000066215"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q34"
                     /cell_line="breast cancer cell line, BT474"
     protein         /gene="CUL4A"
                     /note="cul-4A"
BEGIN
        1 MLYKQLRQAC EDHVQAQILP FREDSLDSVL FLKKINTCWQ DHCRQMIMIR SIFLFLDRTY
       61 VLQNSTLPSI WDMGLELFRT HIISDKMVQS KTIDGILLLI ERERSGEAVD RSLLRSLLGM
      121 LSDLQVYKDS FELKFLEETN CLYAAEGQRL MQEREVPEYL NHVSKRLEEE GDRVITYLDH
      181 STQKPLIACV EKQLLGEHLT AILQKGLDHL LDENRVPDLA QMYQLFSRVR GGQQALLQHW
      241 SEYIKTFGTA IVINPEKDKD MVQDLLDFKD KVDHVIEVCF QKNERFVNLM KESFETFINK
      301 RPNKPAELIA KHVDSKLRAG NKEATDEELE RTLDKIMILF RFIHGKDVFE AFYKKDLAKR
      361 LLVGKSASVD AEKSMLSKLK HECGAAFTSK LEGMFKDMEL SKDIMVHFKQ HMQNQSDSGP
      421 IDLTVNILTM GYWPTYTPME VHLTPEMIKL QEVFKAFYLG KHSGRKLQWQ TTLGHAVLKA
      481 EFKEGKKEFQ VSLFQTLVLL MFNEGDGFSF EEIKMATGIE DSELRRTLQS LACGKARVLI
      541 KSPKGKEVED GDKFIFNGEF KHKLFRIKIN QIQMKETVEE QVSTTERVFQ DRQYQIDAAI
      601 VRIMKMRKTL GHNLLVSELY NQLKFPVKPG DLKKRIESLI DRDYMERDKD NPNQYHYVA
//