LOCUS       AAD17329.1               308 aa    PRT              HUM 14-OCT-1999
DEFINITION  Homo sapiens bisphosphate 3'-nucleotidase protein.
ACCESSION   AF125042-1
PROTEIN_ID  AAD17329.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2113)
  AUTHORS   Spiegelberg,B.D., Xiong,J.P., Smith,J.J., Gu,R.F. and York,J.D.
  TITLE     Cloning and characterization of a mammalian lithium-sensitive
            bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate
  JOURNAL   J. Biol. Chem. 274 (19), 13619-13628 (1999)
   PUBMED   10224133
REFERENCE   2  (bases 1 to 2113)
  AUTHORS   Spiegelberg,B.D. and York,J.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JAN-1999) Pharmacology/Cancer Biology and
            Biochemistry, Duke University, Duke Univ. Medical Center, Box 3813,
            Durham, NC 27708, USA
FEATURES             Qualifiers
     source          /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     protein         /function="3' phosphomonoesterase activity on PAP and
                     PAPS"
                     /note="BPntase; lithium-sensitive nucleotidase; inhibited
                     by inositol 1,4-bisphosphate; complements yeast met22
                     disruption"
BEGIN
        1 MASSNTVLMR LVASAYSIAQ KAGMIVRRVI AEGDLGIVEK TCATDLQTKA DRLAQMSICS
       61 SLARKFPKLT IIGEEDLPSE EVDQELIEDS QWEEILKQPC PSQYSAIKEE DLVVWVDPLD
      121 GTKEYTEGLL DNVTVLIGIA YEGKAIAGVI NQPYYNYEAG PDAVLGRTIW GVLGLGAFGF
      181 QLKEVPAGKH IITTTRSHSN KLVTDCVAAM NPDAVLRVGG AGNKIIQLIE GKASAYVFAS
      241 PGCKKWDTCA PEVILHAVGG KLTDIHGNVL QYHKDVKHMN SAGVLATLRN YDYYASRVPE
      301 SIKNALVP
//