LOCUS       AAC51866.1               310 aa    PRT              HUM 21-NOV-1997
DEFINITION  Homo sapiens 26S proteasome-associated pad1 homolog protein.
ACCESSION   U86782-1
PROTEIN_ID  AAC51866.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Spataro,V., Toda,T., Craig,R., Seeger,M., Dubiel,W., Harris,A.L.
            and Norbury,C.
  TITLE     Resistance to diverse drugs and ultraviolet light conferred by
            overexpression of a novel human 26 S proteasome subunit
  JOURNAL   J. Biol. Chem. 272 (48), 30470-30475 (1997)
   PUBMED   9374539
REFERENCE   2  (bases 1 to 1132)
  AUTHORS   Norbury,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-1997) ICRF Molecular Oncology Laboratory,
            Institute of Molecular Medicine, John Radcliffe Hospital, Headley
            Way, Oxford OX3 9DS, UK
COMMENT     On May 9, 1997 this sequence version replaced gi:1923255.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000221985"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /cell_type="fibroblast"
                     /tissue_type="lung"
     protein         /gene="POH1"
                     /function="induces multi-drug resistance on
                     overexpression"
                     /note="human homolog of fission yeast pad1"
BEGIN
        1 MDRLLRLGGG MPGLGQGPPT DAPAVDTAEQ VYISSLALLK MLKHGRAGVP MEVMGLMLGE
       61 FVDDYTVRVI DVFAMPQSGT GVSVEAVDPV FQAKMLDMLK QTGRPEMVVG WYHSHPGFGC
      121 WLSGVDINTQ QSFEALSERA VAVVVDPIQS VKGKVVIDAF RLINANMMVL GHEPRQTTSN
      181 LGHLNKPSIQ ALIHGLNRHY YSITINYRKN ELEQKMLLNL HKKSWMEGLT LQDYSEHCKH
      241 NESVVKEMLE LAKNYNKAVE EEDKMTPEQL AIKNVGKQDP KRHLEEHVDV LMTSNIVQCL
      301 AAMLDTVVFK
//