LOCUS       AAB59529.1               412 aa    PRT              HUM 08-AUG-1995
DEFINITION  Homo sapiens CTSD protein.
ACCESSION   M11233-1
PROTEIN_ID  AAB59529.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2038)
  AUTHORS   Faust,P.L., Kornfeld,S. and Chirgwin,J.M.
  TITLE     Cloning and sequence analysis of cDNA for human cathepsin D
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 82 (15), 4910-4914 (1985)
   PUBMED   3927292
COMMENT     Original source text: Human kidney, cDNA to mRNA, clone pHKCD45;
            hepatoma cell line G2 (HepG2), clone lambda-HG2CD1.1.
            There are seven more amino acids encoded by the human mRNA than are
            encoded by the porcine mRNA (positions 535-555).  The extra amino
            acids are found at the junction between the light and heavy chains
            of cathepsin.  It is at present not known where the human protein
            is cleaved to form these two chains.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000194107"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="11p15.5"
     protein         /gene="CTSD"
                     /note="preprocathepsin D"
                     /db_xref="GDB:G00-120-512"
BEGIN
        1 MQPSSLLPLA LCLLAAPASA LVRIPLHKFT SIRRTMSEVG GSVEDLIAKG PVSKYSQAVP
       61 AVTEGPIPEV LKNYMDAQYY GEIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KLLDIACWIH
      121 HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC QSASSASALG GVKVERQVFG
      181 EATKQPGITF IAAKFDGILG MAYPRISVNN VLPVFDNLMQ QKLVDQNIFS FYLSRDPDAQ
      241 PGGELMLGGT DSKYYKGSLS YLNVTRKAYW QVHLDQVEVA SGLTLCKEGC EAIVDTGTSL
      301 MVGPVDEVRE LQKAIGAVPL IQGEYMIPCE KVSTLPAITL KLGGKGYKLS PEDYTLKVSQ
      361 AGKTLCLSGF MGMDIPPPSG PLWILGDVFI GRYYTVFDRD NNRVGFAEAA RL
//