LOCUS       AAB41788.1               787 aa    PRT              HUM 02-FEB-1997
DEFINITION  Homo sapiens smoothened protein.
ACCESSION   U84401-1
PROTEIN_ID  AAB41788.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Stone,D., Hynes,M., Armanini,M., Swanson,T., Gu,Q., Johnson,R.,
            Scott,M., Pennica,D., Goddard,A., Phillips,H., Noll,M., Hooper,J.,
            de Sauvage,F.J. and Rosenthal,A.
  TITLE     The tumour-suppressor gene patched encodes a candidate receptor for
            Sonic hedgehog
  JOURNAL   Nature 384 (6605), 129-134 (1996)
   PUBMED   8906787
REFERENCE   2  (bases 1 to 2364)
  AUTHORS   Stone,D., Hynes,M., Armanini,M., Swanson,T., Gu,Q., Johnson,R.,
            Scott,M., Pennica,D., Goddard,A., Phillips,H., Noll,M., Hooper,J.,
            de Sauvage,F.J. and Rosenthal,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JAN-1997) Molecular Oncology, Genentech Inc., 460 Pt
            San Bruno Blvd., South San Francisco, CA 94404, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000221863"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     protein         /function="candidate receptor for Sonic hedgehog"
BEGIN
        1 MAAARPARGP ELPLLGLLLL LLLGDPGRGA ASSGNATGPG PRSAGGSARR SAAVTGPPPP
       61 LSHCGRAAPC EPLRYNVCLG SVLPYGATST LLAGDSDSQE EAHGKLVLWS GLRNAPRCWA
      121 VIQPLLCAVY MPKCENDRVE LPSRTLCQAT RGPCAIVERE RGWPDFLRCT PDRFPEGCTN
      181 EVQNIKFNSS GQCEVPLVRT DNPKSWYEDV EGCGIQCQNP LFTEAEHQDM HSYIAAFGAV
      241 TGLCTLFTLA TFVADWRNSN RYPAVILFYV NACFFVGSIG WLAQFMDGAR REIVCRADGT
      301 MRLGEPTSNE TLSCVIIFVI VYYALMAGVV WFVVLTYAWH TSFKALGTTY QPLSGKTSYF
      361 HLLTWSLPFV LTVAILAVAQ VDGDSVSGIC FVGYKNYRYR AGFVLAPIGL VLIVGGYFLI
      421 RGVMTLFSIK SNHPGLLSEK AASKINETML RLGIFGFLAF GFVLITFSCH FYDFFNQAEW
      481 ERSFRDYVLC QANVTIGLPT KQPIPDCEIK NRPSLLVEKI NLFAMFGTGI AMSTWVWTKA
      541 TLLIWRRTWC RLTGQSDDEP KRIKKSKMIA KAFSKRHELL QNPGQELSFS MHTVSHDGPV
      601 AGLAFDLNEP SADVSSAWAQ HVTKMVARRG AILPQDISVT PVATPVPPEE QANLWLVEAE
      661 ISPELQKRLG RKKKRRKRKK EVCPLAPPPE LHPPAPAPST IPRLPQLPRQ KCLVAAGAWG
      721 AGDSCRQGAW TLVSNPFCPE PSPPQDPFLP SAPAPVAWAH GRRQGLGPIH SRTNLMDTEL
      781 MDADSDF
//