LOCUS       AAB37227.1               529 aa    PRT              HUM 02-DEC-1996
DEFINITION  Homo sapiens tyrosinase precursor protein.
ACCESSION   M27160-1
PROTEIN_ID  AAB37227.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 601 to 2384)
  AUTHORS   Shibahara,S., Tomita,Y., Tagami,H., Muller,R.M. and Cohen,T.
  TITLE     Molecular basis for the heterogeneity of human tyrosinase
  JOURNAL   Tohoku J. Exp. Med. 156 (4), 403-414 (1988)
   PUBMED   2854305
REFERENCE   2  (bases 1 to 600)
  AUTHORS   Takeda,A., Tomita,Y., Okinaga,S., Tagami,H. and Shibahara,S.
  TITLE     Functional analysis of the cDNA encoding human tyrosinase precursor
  JOURNAL   Biochem. Biophys. Res. Commun. 162 (3), 984-990 (1989)
   PUBMED   2504160
COMMENT     On Dec 2, 1996 this sequence version replaced gi:340036.
            Draft entry and computer-readable copy of sequence [1] kindly
            provided by S.Shibahara, 15-AUG-1989.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000195113"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14-q21"
                     /cell_line="MeWo melanoma DNA, and cDNA to mRNA"
                     /tissue_type="placenta"
     protein         /gene="TYR"
                     /EC_number="1.14.18.1"
                     /db_xref="GDB:G00-120-476"
BEGIN
        1 MLLAVLYCLL WSFQTSAGHF PRACVSSKNL MEKECCPPWS GDRSPCGQLS GRGSCQNILL
       61 SNAPLGPQFP FTGVDDRESW PSVFYNRTCQ CSGNFMGFNC GNCKFGFWGP NCTERRLLVR
      121 RNIFDLSAPE KDKFFAYLTL AKHTISSDYV IPIGTYGQMK NGSTPMFNDI NIYDLFVWMH
      181 YYVSMDALLG GSEIWRDIDF AHEAPAFLPW HRLFLLRWEQ EIQKLTGDEN FTIPYWDWRD
      241 AEKCDICTDE YMGGQHPTNP NLLSPASFFS SWQIVCSRLE EYNSHQSLCN GTPEGPLRRN
      301 PGNHDKSRTP RLPSSADVEF CLSLTQYESG SMDKAANFSF RNTLEGFASP LTGIADASQS
      361 SMHNALHIYM NGTMSQVQGS ANDPIFLLHH AFVDSIFEQW LRRHRPLQEV YPEANAPIGH
      421 NRESYMVPFI PLYRNGDFFI SSKDLGYDYS YLQDSDPDSF QDYIKSYLEQ ASRIWSWLLG
      481 AAMVGAVLTA LLAGLVSLLC RHKRKQLPEE KQPLLMEKED YHSLYQSHL
//