LOCUS       AAA97891.1               507 aa    PRT              HUM 25-SEP-2002
DEFINITION  Homo sapiens cAMP-specific phosphodiesterase HPDE4D2 variant
            protein.
ACCESSION   U50158-1
PROTEIN_ID  AAA97891.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1684)
  AUTHORS   Swinnen,J.V., Joseph,D.R. and Conti,M.
  TITLE     The mRNA encoding a high-affinity cAMP phosphodiesterase is
            regulated by hormones and cAMP
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 86 (21), 8197-8201 (1989)
   PUBMED   2554303
REFERENCE   2  (bases 1 to 1684)
  AUTHORS   Nemoz,G., Zhang,R., Sette,C. and Conti,M.
  TITLE     Identification of cyclic AMP-phosphodiesterase variants from the
            PDE4D gene expressed in human peripheral mononuclear cells
  JOURNAL   FEBS Lett. 384 (1), 97-102 (1996)
   PUBMED   8797812
REFERENCE   3  (bases 1 to 1684)
  AUTHORS   Conti,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-1996) Marco Conti, Gynecology and Obstetrics,
            Stanford University, 300 Pasteur Dr, Stanford, CA 94305-5317, USA
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000220135"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q11"
     protein         /gene="PDE4D"
BEGIN
        1 MASNKFKRML NRELTHLSEM SRSGNQVSEF ISNTFLDKQH EVEIPSPTQK EKEKKKRPMS
       61 QISGVKKLMH SSSLTNSSIP RFGVKTEQED VLAKELEDVN KWGLHVFRIA ELSGNRPLTV
      121 IMHTIFQERD LLKTFKIPVD TLITYLMTLE DHYHADVAYH NNIHAADVVQ STHVLLSTPA
      181 LEAVFTDLEI LAAIFASAIH DVDHPGVSNQ FLINTNSELA LMYNDSSVLE NHHLAVGFKL
      241 LQEENCDIFQ NLTKKQRQSL RKMVIDIVLA TDMSKHMNLL ADLKTMVETK KVTSSGVLLL
      301 DNYSDRIQVL QNMVHCADLS NPTKPLQLYR QWTDRIMEEF FRQGDRERER GMEISPMCDK
      361 HNASVEKSQV GFIDYIVHPL WETWADLVHP DAQDILDTLE DNREWYQSTI PQSPSPAPDD
      421 PEEGRQGQTE KFQFELTLEE DGESDTEKDS GSQVEEDTSC SDSKTLRTQD SESTEIPLDE
      481 QVEEEAVGEE EESQPEACVI DDRSPDT
//