LOCUS       AAA59964.2               968 aa    PRT              HUM 08-MAR-2001
DEFINITION  Homo sapiens Lowe oculocerebrorenal syndrome protein protein.
ACCESSION   M88162-1
PROTEIN_ID  AAA59964.2
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4353)
  AUTHORS   Attree,O., Olivos,I.M., Okabe,I., Bailey,L.C., Nelson,D.L.,
            Lewis,R.A., McInnes,R.R. and Nussbaum,R.L.
  TITLE     The Lowe's oculocerebrorenal syndrome gene encodes a protein highly
            homologous to inositol polyphosphate-5-phosphatase
  JOURNAL   Nature 358 (6383), 239-242 (1992)
   PUBMED   1321346
REFERENCE   2  (bases 1 to 4353)
  AUTHORS   Attree,O., Olivos,I.M., Okabe,I., Bailey,L.C., Nelson,D.L.,
            Lewis,R.A., McInnes,R.R. and Nussbaum,R.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-1992) Department of Human Genetics, University of
            Pennsylvania School of Medicine, Philadelphia, PA 19104-6145, USA
REFERENCE   3  (bases 1 to 4353)
  AUTHORS   Nussbaum,R.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAR-2001) Genetic Disease Research Branch, NHGRI,
            NIH, 49 Convent Drive MSC4472, Bethesda, MD 20892-4472, USA
  REMARK    Sequence update by submitter
COMMENT     On Mar 8, 2001 this sequence version replaced M88162.1.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000196693"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq25-q26.1"
                     /tissue_type="kidney"
     protein         /gene="OCRL"
                     /note="similar to inositol polyphosphate-5-phophatase"
                     /db_xref="GDB:G00-119-461"
BEGIN
        1 MKFFVFKSFL SDCYRSLLDK SQLPAPRSRL PAPGARRGAV PQTTRSRGGW VWGRGSQCRR
       61 IGPQSAVLLS PEAAWMEPPL PVGAQPLATV EGMEMKGPLR EPCALTLAQR NGQYELIIQL
      121 HEKEQHVQDI IPINSHFRCV QEAEETLLID IASNSGCKIR VQGDWIRERR FEIPDEEHCL
      181 KFLSAVLAAQ KAQSQLLVPE QKDSSSWYQK LDTKDKPSVF SGLLGFEDNF SSMNLDKKIN
      241 SQNQPTGIHR EPPPPPFSVN KMLPREKEAS NKEQPKVTNT MRKLFVPNTQ SGQREGLIKH
      301 ILAKREKEYV NIQTFRFFVG TWNVNGQSPD SGLEPWLNCD PNPPDIYCIG FQELDLSTEA
      361 FFYFESVKEQ EWSMAVERGL HSKAKYKKVQ LVRLVGMMLL IFARKDQCRY IRDIATETVG
      421 TGIMGKMGNK GGVAVRFVFH NTTFCIVNSH LAAHVEDFER RNQDYKDICA RMSFVVPNQT
      481 LPQLNIMKHE VVIWLGDLNY RLCMPDANEV KSLINKKDLQ RLLKFDQLNI QRTQKKAFVD
      541 FNEGEIKFIP TYKYDSKTDR WDSSGKCRVP AWCDRILWRG TNVNQLNYRS HMELKTSDHK
      601 PVSALFHIGV KVVDERRYRK VFEDSVRIMD RMENDFLPSL ELSRREFVFE NVKFRQLQKE
      661 KFQISNNGQV PCHFSFIPKL NDSQYCKPWL RAEPFEGYLE PNETVDISLD VYVSKDSVTI
      721 LNSGEDKIED ILVLHLDRGK DYFLTISGNY LPSCFGTSLE ALCRMKRPIR EVPVTKLIDL
      781 EKSLLQMVPL DEGASERPLQ VPKEIWLLVD HLFKYACHQE DLFQTPGMQE ELQQIIDCLD
      841 TSIPETIPGS NHSVAEALLI FLEALPEPVI CYELYQRCLD SAYDPRICRQ VISQLPRCHR
      901 NVFRYLMAFL RELLKFSEYN SVNANMIATL FTSLLLRPPP NLMARQTPSD RQRAIQFLLG
      961 FLLGSEED
//