LOCUS       AAA52153.1               497 aa    PRT              HUM 02-NOV-1994
DEFINITION  Homo sapiens CYP2D protein.
ACCESSION   M20403-1
PROTEIN_ID  AAA52153.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1567)
  AUTHORS   Gonzalez,F.J., Vilbois,F., Hardwick,J.P., McBride,O.W.,
            Nebert,D.W., Gelboin,H.V. and Meyer,U.A.
  TITLE     Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino
            acid sequence and assignment of the CYP2D locus to chromosome 22
  JOURNAL   Genomics 2 (2), 174-179 (1988)
   PUBMED   3410476
COMMENT     Original source text: Human hepatocyte, cDNA to mRNA.
            Draft entry and printed copy of sequence for [1] kindly provided by
            D.W.Nebert, 15-JUL-1988.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000194724"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="22q11.2-qter"
     protein         /gene="CYP2D"
                     /note="debrisoquine 4-hydroxylase"
                     /db_xref="GDB:G00-119-832"
BEGIN
        1 MGLEALVPLA VIVAIFLLLV DLMHRRQRWA ARYPPGPLPL PGLGNLLHVD FQNTPYCFDQ
       61 LRRRFGDVFS LQLAWTPVVV LNGLAAVREA LVTHGEDTAD RPPVPITQIL GFGPRSQGVF
      121 LARYGPAWRE QRRFSVSTLR NLGLGKKSLE QWVTEEAACL CAAFANHSGR PFRPNGLLDK
      181 AVSNVIASLT CGRRFEYDDP RFLRLLDLAQ EGLKEESGFL REVLNAVPVL LHIPALAGKV
      241 LRFQKAFLTQ LDELLTEHRM TWDPAQPPRD LTEAFLAEME KAKGNPESSF NDENLRIVVA
      301 DLFSAGMVTT STTLAWGLLL MILHPDVQRR VQQEIDDVIG QVRRPEMGDQ AHMPYTTAVI
      361 HEVQRFGDIV PLGMTHMTSR DIEVQGFRIP KGTTLITNLS SVLKDEAVWE KPFRFHPEHF
      421 LDAQGHFVKP EAFLPFSAGR RACLGEPLAR MELFLFFTSL LQHFSFSVPT GQPRPSHHGV
      481 FAFLVSPSPY ELCAVPR
//