LOCUS       AAA16069.1               458 aa    PRT              HUM 24-JAN-1994
DEFINITION  Homo sapiens CD4 protein.
ACCESSION   M35160-1
PROTEIN_ID  AAA16069.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Hodge,T.W., Sasso,D.R. and McDougal,J.S.
  TITLE     Humans with OKT4-epitope deficiency have a single nucleotide base
            change in the CD4 gene, resulting in substitution of TRP240 for
            ARG240
  JOURNAL   Hum. Immunol. 30 (2), 99-104 (1991)
   PUBMED   1708753
REFERENCE   2  (bases 1 to 1742)
  AUTHORS   Hodge,T.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-1990) T.W. Hodge, A-25 Bldg. 1, Rm. 1226, Centers
            for Disease Control, 1600 Clifton Rd. Atlanta, GA 30333 USA
COMMENT     A cytosine to thymidine transition at nucleotide position 868
            results in substitution of TRP-240 for ARG-240.
FEATURES             Qualifiers
     source          /organism="Homo sapiens"
                     /mol_type="unassigned DNA"
                     /db_xref="taxon:9606"
                     /haplotype="OKT4-negative"
     protein         /gene="CD4"
                     /note="T4 surface glycoprotein precursor"
BEGIN
        1 MNRGVPFRHL LLVLQLALLP AATQGKKVVL GKKGDTVELT CTASQKKSIQ FHWKNSNQIK
       61 ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VEDQKEEVQL
      121 LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS VSQLELQDSG
      181 TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE KLTGSGELWW
      241 QAERASSSKS WITFDLKNKE VSVKWVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLA
      301 LEAKTGKLHQ EVNLVVMRAT QLQKNLTCEV WGPTSPKLML SLKLENKEAK VSKREKAVWV
      361 LNPEAGMWQC LLSDSGQVLL ESNIKVLPTW STPVQPMALI VLGGVAGLLL FIGLGIFFCV
      421 RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR FQKTCSPI
//