LOCUS CAB13622.1 700 aa PRT BCT 08-FEB-2018 DEFINITION Bacillus subtilis subsp. subtilis str. 168 ribonucleoside- diphosphate reductase (major subunit) protein. ACCESSION AL009126-1816 PROTEIN_ID CAB13622.1 SOURCE Bacillus subtilis subsp. subtilis str. 168 ORGANISM Bacillus subtilis subsp. subtilis str. 168 Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. REFERENCE 1 (bases 1 to 4215606) AUTHORS Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.K., Codani J.J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Dusterhoft A., Ehrlich S.D., Emmerson P.T., Entian K.D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.F., Itaya M., Jones L., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.F., Zumstein E., Yoshikawa H., Danchin A. TITLE The complete genome sequence of the gram-positive bacterium Bacillus subtilis JOURNAL Nature 390(6657), 249-256(1997). PUBMED 9384377 REFERENCE 2 (bases 1 to 4215606) AUTHORS Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A. TITLE From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later JOURNAL Microbiology (Reading, Engl.) 155(Pt 6), 1758-1775(2009). PUBMED 19383706 REFERENCE 3 (bases 1 to 4215606) AUTHORS Belda E., Sekowska A., Le Fevre F., Mornico D., Morgat A., Ouzounis C., Vallenet D., Medigue C., Danchin A. TITLE An updated metabolic view of the Bacillus subtilis 168 genome JOURNAL Microbiology (Reading, Engl.) 159(Pt 4), 757-770(2013). PUBMED 23429746 REFERENCE 4 (bases 1 to 4215606) AUTHORS Kunst F., Ogasawara N., Yoshikawa H., Danchin A. JOURNAL Submitted (18-NOV-1997) to the INSDC. I. Moszer, A. Danchin, Genetique des Genomes Bacteriens, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, FRANCE. E-mail: moszer@pasteur.fr, antoine.danchin@normalesup.org Phone: +33 (0)1 45 68 84 41, Fax: +33 (0)1 45 68 89 48 REFERENCE 5 (bases 1 to 4215606) AUTHORS Genoscope - C.E.A. CONSRTM Institut Pasteur and Genoscope JOURNAL Submitted (29-JAN-2009) to the INSDC. Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr) REFERENCE 6 (bases 1 to 4215606) AUTHORS Genoscope - C.E.A. CONSRTM AMAbiotics and Genoscope JOURNAL Submitted (24-JAN-2013) to the INSDC. A. Danchin, AMAbiotics, Bldg G1, 2, rue Gaston Cremieux, 91000 EVRY antoine.danchin@normalesup.org Bldg G1 Genoscope / CEA (Commissariat a l'energie atomique et aux energies alternatives): BP 191 91006 EVRY cedex - FRANCE (E-mail: seqref@genoscope.cns.fr - Web: www.genoscope.cns.fr) REFERENCE 8 AUTHORS Borriss R., Danchin A., Harwood C.R., Medigue C., Rocha E.P.C., Sekowska A., Vallenet D. TITLE Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement JOURNAL Microb Biotechnol 11(1), 3-17(2018). PUBMED 29280348 COMMENT On or before Mar 17, 2009 this sequence version replaced gi:32468687, gi:32468690, gi:32468695, gi:32468704, gi:32468715, gi:32468723, gi:32468738, gi:32468743, gi:32468745, gi:32468758, gi:32468767, gi:32468778, gi:32468787, gi:32468796, gi:32468802, gi:32468809, gi:32468813, gi:32468825, gi:32468830, gi:32468833, gi:32468840, gi:38680335. Annotation results relative to BLAST similarities, COG assignations, enzymatic function prediction (PRIAM software), TMHMM and SignalP predictions, and synteny conservation (Syntonizer software) are available in the MicroScope annotation platform http://www.genoscope.cns.fr/agc/microscope. The large cluster comprising the i, h and g rDNA regions could not be properly resolved, we therefore incorporated the original sequence of rRNAihg in the final assembly. FEATURES Qualifiers source /organism="Bacillus subtilis subsp. subtilis str. 168" /sub_species="subtilis" /strain="168" /mol_type="genomic DNA" /db_xref="taxon:224308" protein /transl_table=11 /gene="nrdE" /locus_tag="BSU_17380" /old_locus_tag="BSU17380" /function="16.2: Construct biomass (Anabolism)" /EC_number="1.17.4.1" /note="Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297; Product type e: enzyme" /db_xref="EnsemblGenomes-Gn:BSU17380" /db_xref="EnsemblGenomes-Tr:CAB13622" /db_xref="GOA:P50620" /db_xref="InterPro:IPR000788" /db_xref="InterPro:IPR008926" /db_xref="InterPro:IPR013346" /db_xref="InterPro:IPR013509" /db_xref="InterPro:IPR013554" /db_xref="InterPro:IPR026459" /db_xref="InterPro:IPR039718" /db_xref="PDB:6CGL" /db_xref="PDB:6CGM" /db_xref="PDB:6CGN" /db_xref="SubtiList:BG11404" /db_xref="UniProtKB/Swiss-Prot:P50620" /experiment="publication(s) with functional evidences, PMID:12682299, 15937154, 16885274, 17395719, 21561096, 22443445, 23402532, 24401092, 27920297" BEGIN 1 MSQNQVPKWI QLNNEIMIQK DGKFQFDKDK EAVHSYFVDY INQNTVFFHN LKEKLDYLVE 61 NQYYEEEFLS LYSFEDIKEV FKTAYAKKFR FPSFMSAFKF YNDYALKTND KKKILERYED 121 RISIVALFFA NGDTEKAKEY VNLMINQEYQ PSTPTFLNAG RKRRGELVSC FLLEVNDSLN 181 DISRAIDISM QLSKLGGGVS LNLSKLRAKG EAIKDVENAT KGVVGVMKLL DNAFRYADQM 241 GQRQGSGAAY LNIFHRDIND FLDTKKISAD EDVRVKTLSI GVVIPDKFVE LAREDKAAYV 301 FYPHTIYKEY GQHMDEMDMN EMYDKFVDNP RVKKEKINPR KLLEKLAMLR SESGYPYIMF 361 QDNVNKVHAN NHISKVKFSN LCSEVLQASQ VSSYTDYDEE DEIGLDISCN LGSLNILNVM 421 EHKSIEKTVK LATDSLTHVS ETTDIRNAPA VRRANKAMKS IGLGAMNLHG YLAQNGIAYE 481 SPEARDFANT FFMMVNFYSI QRSAEIAKEK GETFDQYEGS TYATGEYFDK YVSTDFSPKY 541 EKIANLFEGM HIPTTEDWKK LKAFVAEHGM YHSYRLCIAP TGSISYVQSS TASVMPIMER 601 IEERTYGNSK TYYPMPGLAS NNWFFYKEAY DMDMFKVVDM IATIQQHIDQ GISFTLFLKD 661 TMTTRDLNRI DLYAHHRGIK TIYYARTKDT GQDSCLSCVV //