LOCUS CAB13603.3 4262 aa PRT BCT 08-FEB-2018
DEFINITION Bacillus subtilis subsp. subtilis str. 168 trans AT polyketide
synthase of type I involved in bacillaene synthesis protein.
ACCESSION AL009126-1796
PROTEIN_ID CAB13603.3
SOURCE Bacillus subtilis subsp. subtilis str. 168
ORGANISM Bacillus subtilis subsp. subtilis str. 168
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE 1 (bases 1 to 4215606)
AUTHORS Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
Borriss R., Boursier L., Brans A., Braun M., Brignell S.C.,
Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V.,
Carter N.M., Choi S.K., Codani J.J., Connerton I.F., Cummings N.J.,
Daniel R.A., Denizot F., Devine K.M., Dusterhoft A., Ehrlich S.D.,
Emmerson P.T., Entian K.D., Errington J., Fabret C., Ferrari E.,
Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A.,
Galleron N., Ghim S.Y., Glaser P., Goffeau A., Golightly E.J.,
Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R.,
Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.F.,
Itaya M., Jones L., Joris B., Karamata D., Kasahara Y.,
Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P.,
Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A.,
Lardinois S., Lauber J., Lazarevic V., Lee S.M., Levine A., Liu H.,
Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P.,
Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M.,
Ogawa K., Ogiwara A., Oudega B., Park S.H., Parro V., Pohl T.M.,
Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P.,
Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M.,
Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T.,
Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
Sekowska A., Seror S.J., Serror P., Shin B.S., Soldo B.,
Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K.,
Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A.,
Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A.,
Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T.,
Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K.,
Yoshida K., Yoshikawa H.F., Zumstein E., Yoshikawa H., Danchin A.
TITLE The complete genome sequence of the gram-positive bacterium
Bacillus subtilis
JOURNAL Nature 390(6657), 249-256(1997).
PUBMED 9384377
REFERENCE 2 (bases 1 to 4215606)
AUTHORS Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G.,
Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C.,
Danchin A.
TITLE From a consortium sequence to a unified sequence: the Bacillus
subtilis 168 reference genome a decade later
JOURNAL Microbiology (Reading, Engl.) 155(Pt 6), 1758-1775(2009).
PUBMED 19383706
REFERENCE 3 (bases 1 to 4215606)
AUTHORS Belda E., Sekowska A., Le Fevre F., Mornico D., Morgat A.,
Ouzounis C., Vallenet D., Medigue C., Danchin A.
TITLE An updated metabolic view of the Bacillus subtilis 168 genome
JOURNAL Microbiology (Reading, Engl.) 159(Pt 4), 757-770(2013).
PUBMED 23429746
REFERENCE 4 (bases 1 to 4215606)
AUTHORS Kunst F., Ogasawara N., Yoshikawa H., Danchin A.
JOURNAL Submitted (18-NOV-1997) to the INSDC. I. Moszer, A. Danchin,
Genetique des Genomes Bacteriens, Institut Pasteur, 28 rue du
Docteur Roux, 75724 Paris Cedex 15, FRANCE. E-mail:
moszer@pasteur.fr, antoine.danchin@normalesup.org Phone: +33 (0)1
45 68 84 41, Fax: +33 (0)1 45 68 89 48
REFERENCE 5 (bases 1 to 4215606)
AUTHORS Genoscope - C.E.A.
CONSRTM Institut Pasteur and Genoscope
JOURNAL Submitted (29-JAN-2009) to the INSDC. Genoscope - Centre National
de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail :
seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
REFERENCE 6 (bases 1 to 4215606)
AUTHORS Genoscope - C.E.A.
CONSRTM AMAbiotics and Genoscope
JOURNAL Submitted (24-JAN-2013) to the INSDC. A. Danchin, AMAbiotics, Bldg
G1, 2, rue Gaston Cremieux, 91000 EVRY
antoine.danchin@normalesup.org Bldg G1 Genoscope / CEA
(Commissariat a l'energie atomique et aux energies alternatives):
BP 191 91006 EVRY cedex - FRANCE (E-mail: seqref@genoscope.cns.fr -
Web: www.genoscope.cns.fr)
REFERENCE 8
AUTHORS Borriss R., Danchin A., Harwood C.R., Medigue C., Rocha E.P.C.,
Sekowska A., Vallenet D.
TITLE Bacillus subtilis, the model Gram-positive bacterium: 20 years of
annotation refinement
JOURNAL Microb Biotechnol 11(1), 3-17(2018).
PUBMED 29280348
COMMENT On or before Mar 17, 2009 this sequence version replaced
gi:32468687, gi:32468690, gi:32468695, gi:32468704, gi:32468715,
gi:32468723, gi:32468738, gi:32468743, gi:32468745, gi:32468758,
gi:32468767, gi:32468778, gi:32468787, gi:32468796, gi:32468802,
gi:32468809, gi:32468813, gi:32468825, gi:32468830, gi:32468833,
gi:32468840, gi:38680335.
Annotation results relative to BLAST similarities, COG
assignations, enzymatic function prediction (PRIAM software), TMHMM
and SignalP predictions, and synteny conservation (Syntonizer
software) are available in the MicroScope annotation platform
http://www.genoscope.cns.fr/agc/microscope.
The large cluster comprising the i, h and g rDNA regions could not
be properly resolved, we therefore incorporated the original
sequence of rRNAihg in the final assembly.
FEATURES Qualifiers
source /organism="Bacillus subtilis subsp. subtilis str. 168"
/sub_species="subtilis"
/strain="168"
/mol_type="genomic DNA"
/db_xref="taxon:224308"
protein /transl_table=11
/gene="pksM"
/locus_tag="BSU_17200"
/old_locus_tag="BSU17200"
/function="16.5: Explore"
/function="16.8: Protect"
/note="Evidence 1a: Function from experimental evidences
in the studied strain; PubMedId: 15480790, 16707694,
17234808, 26284661; Product type e: enzyme"
/db_xref="EnsemblGenomes-Gn:BSU17200"
/db_xref="EnsemblGenomes-Tr:CAB13603"
/db_xref="GOA:P40872"
/db_xref="InterPro:IPR006162"
/db_xref="InterPro:IPR009081"
/db_xref="InterPro:IPR013217"
/db_xref="InterPro:IPR013968"
/db_xref="InterPro:IPR014030"
/db_xref="InterPro:IPR014031"
/db_xref="InterPro:IPR016039"
/db_xref="InterPro:IPR018201"
/db_xref="InterPro:IPR020615"
/db_xref="InterPro:IPR020806"
/db_xref="InterPro:IPR020807"
/db_xref="InterPro:IPR020841"
/db_xref="InterPro:IPR029063"
/db_xref="InterPro:IPR032821"
/db_xref="InterPro:IPR036291"
/db_xref="InterPro:IPR036736"
/db_xref="InterPro:IPR042104"
/db_xref="SubtiList:BG10931"
/db_xref="UniProtKB/Swiss-Prot:P40872"
/experiment="publication(s) with functional evidences,
PMID:15480790, 16707694, 17234808, 26284661"
BEGIN
1 MITEQLHISL NNPIMSNHKV YGQALLPGLA YIDLIYQVFQ EHGYAYQELE LKNLTIFYPL
61 IADESYDIAL TIHVSERKEG TWSIIIDGQK QHGESLSDKR QYVTADMHRK EQTAFAESID
121 LNQWKSTADR ILNLDEIYEQ CRSQELVHTG MMKAEGQIYE AKEGAVIDLA VGQEALRHSD
181 AFLFHPTLID GSGIGSSCLI SDQTMYLPLY YESFSASERL QKGCTARILS SSVRQKKELT
241 YMTIEYFNSA GQKVAELKQF AGKSVRNMSA FHSAKEIQEE RAAVSQNISR DYPAFEMYLR
301 QLLAKQLERP AEQMDIHAGY YELGLDSSSL LTVVQEIGDK VGADLAPTLL FEFTTIAELA
361 AHLADHYSIG EADDAVRQSP SPIDGVTSSP EIGEDIAIIG MAGRYPKAKN IQEFWEQLKA
421 GTDCITEIPN SRWEWKESDG LDSPAGKPLS KWGGFIEEAD CFDPQFFRIS PREAEMMDPQ
481 ERLFLETCWE AIEDAGYTPE TIASPQGENK RQHVGVFAGV MHKDYSLIGA EALSEHNPFP
541 LSLNYAQIAN RVSYYCNFHG PSMAVDTVCS SSLTAVHLAI ESIRNGECEA ALAGGVNLSL
601 HPAKYISYGS VGMHSSDGYC HTFGKGGDGY VSGEGVGTVL LKPLRKAEQD GDRIYAVIKG
661 SAINHVGKVS GITVPSPVAQ ADVIEACLEK TGIDPRTISY VEAHGTGTSL GDPIEVQGLV
721 KAFSRNTQDK QFCSIGSVKS NIGHAEAAAG ISGLTKTVLQ LHHKTLVPSL HSEELNPYLK
781 LDQTPFFVQH ETKEWEQPSF TENGVDVTYP RRAGLSSFGA SGSNAHLILE EYIPAESHSE
841 TILTKNEEIV IPLSARNKDR LQAYALKLLD FLSEDVNLLA LAYTMQAGRV EMEERAAFIV
901 KDIKDLTAKL RAFANGEEEI EGCWTGRAKE NQEAAGLASV NALNNNLIRD SEMMEMAKAW
961 VQGKRVTWDD LYGDRKPLKI SVPTYPFARE RYWISVPEMK TSTVNHILHP LVHRNTSDFT
1021 EQRFSSVFTG TEFFLSDHVV QGQKILPGVA YLEMAREAAE KAAGDLDGEQ RVVSLKDIVW
1081 VRPITIESEP KEIHIGLFPE DNGDISFDIY SSSEHKEEAL TIHCQGRAVI SDEAETSILN
1141 LSSIQTECSL DTVTSEQCYA AFRKIGLDYG EGYQGIEKVY VGKDQLLAKI SLPAFLKNDK
1201 QHFALHPSLM DSAFHATVGF IVSSVNAAGQ AQTLSLPFAL QEVDIFSPCP EKIWSYIRYS
1261 SDSKAENKVR KYDIDLCDEN GRVCVRMKGA SMRALDGEQH SKPQLLTDSQ LTGHTVMIPV
1321 WEPVSLEAED NASFAGKRAV LCGAAEADRT FIKHHYPQIS FVDIRPADDI EAIADKLQAY
1381 GSIDHVLWIA PSHRGSIGSD GQEEAVLHLF KLVKACLQLG YGEKQLEWSL VTVQAQPVTQ
1441 HEAVQPAHAS IHGLAGTMAK EYPHWKIRLL DLEKGCTWPV NHMFALPADR LGHAWAYRNQ
1501 QWHQQQLIPY RSSLSGDTLY RKGGVYVVIG GAGYIGEAWS EYMIRRYQAQ IVWIGRSQLN
1561 AAIQSKIDRL SALGPEPFYI AADAADKHSL QQAYEQVKKR HPHIHGIVHS AMVLFEQSLE
1621 KMKPEEFTAG LAAKIDVSIR MAQVFRQENV DFVLFFSSLV AHIKNVKQSH YASGCTFADA
1681 FAHQLSQSWA CPVKVMNWGY WGNSEAAEDE HYVQLMNQIG LGLIEPAEAM KALEALLSGP
1741 VSQTAFIHTT KPVAVEGVNQ NEFITLYPEQ PSADAESLME RLPTTGRFQR VTHEELDDLL
1801 YRLLLGQLQT AELFDGYTLS VERLQQYKTR EFYGKWIRQS SEFLLQHGYL KKVGDSLVRK
1861 DQAEDIELLW LEWNAKKEKW LKDSETKAMV VLAEAMLQAL PDILTGKVPA TDIMFPHSSM
1921 ELVEGIYKHN QVADYFNKVL ADTLLAYLDE RLKHDPEASI RIMEIGAGTG GTSAGIFEKL
1981 KPYQKHINEY CYTDLSKAFL LHAEKEYGAE NPYLTYQLFD VEKPIDQQEF EAGGYDVVIA
2041 ANVLHATKNI RQTLRHTKAV MKNNGMLLLN EMAGNSLFPH ITFGLLEGWW LYEDPAVRIP
2101 GCPGLHPDSW KAALESEGFE SVFFPAEAAH DLSHQIVAAS SNGLVRRMMK NVILPEKVVS
2161 QASNQEPAYI HTIDSEEAGQ SKHALLREKS TEYMKKLIGE TLKIPAGKIE SSEPLEKYGI
2221 DSIVVVQLTN TLRKEFDHVS STLFFEYQTI DALVEHFIKT KTEALMKLTG LDRQVQQHTP
2281 AESRTQSSQK PDQAAKRTRR FRKLGFSGEK ETPTNTLASR DVAVIGISGR YPQAETAEDF
2341 WNNLKEGRNC IEEIPKDRWD WKAYYDKEKG KEGSIYTKWG GFIKDMDKFD PLFFQISPLE
2401 AERMDPQERL FLQTAYASIE DAGYTPDSLC SSRKIGVFAG VMNKNYPTGY GYWSIANRIS
2461 YLLNFQGPSL AVDTACSSSL TAIHLALESI YSGSSDCAIA GGVNLVVDPV HYQNLSVMNM
2521 LSASDTCKSF GDDADGFVDG EGVGAIVLKP LQQAIADGDH IYGVIKASAI NSGGKTNGYT
2581 VPNPHAQAQV IKEAIERADI PARTISYLEA HGTGTALGDP IEIAGLTKAF EKDTQEKQFC
2641 AIGSSKSNIG HCESAAGIAG LTKILFQFKY GQIAPSLHAQ RLNPNIEFSH TPFVVQQQLG
2701 EWKRPVIGGQ EVPRRAGLSS FGAGGSNAHI ILEEYIPRTG AQTPKDHPPA LIVLSAKNME
2761 RLQEKAEQLL TAIKQKRYCE TDLIRIAYTL QTGREAMEER LAFIAESLED LERKLNDFIE
2821 NKADSLYLDR IDDNKKALAV LSADEDTEKI IEAWMSKGKY TKLLDLWVKG LSFDWGMLYG
2881 TQTPVRISLP AYPFAKERYW APGAAKAPVS IEQDHDQQTE EPFKVMTFQE VWKEEPATLT
2941 SKRIKTLICF LTEREKQNAF ASALKNVDQD TKVIFISQGE VYSKQSEYSY QIVRQEPVTF
3001 EKAFQSIKEE LGEPDAILYM WPMEDKRCIK DHSCIVYLLQ GMSAAKLHPS RLLLAGCFED
3061 SLDRSYLESW IGFERSLGLV LPHTKVTGIF QPAEQGSMDD WTRKVWAELQ ASTEQTVLYQ
3121 NLKRYVNHIE QTTIQPDNSK LKSGGTYLIT GGVGGLGYLF AKHLAKNYAA NLILTGRSPF
3181 NDEKQKQIKE LKDLGGEAMY AEADVSDPIA MGDCVKRGKD RFGAINGVIH AAGIESDSAI
3241 FDKKIESFQR IIEPKINGTI ALDEWLKNED LDFMCYFSSS SAVLGDFGCC DYAIGNRFQM
3301 AYAQYRNELH NGKTFVINWP VWKDGGMKIG DEETTDMYLK SSGQRFLEAE EGIRMFEHIL
3361 AQQDAQHLVI AGQPSRVSRF LGMTEPAIPE PATQAPLAQE NKDEVKTLSI EKRLEHDLKE
3421 HIHTLLKISK DKLNLNKNWA DFGFDSIYLA KFSNVLSKHF NIEVTPALFF GYSTLQELIS
3481 FFLTDHKELI EAFYRDDASE AQKPPEAYAV IPVALEPEAS KKSIRQVHDE PIAIIGMSGR
3541 FPQADSVHEL WDNLKNGKSC ISDIPGERRD WGRANRDPEK AVPRWGAFLK DIDRFDPLFF
3601 QISPKEAESM DPRQRIFLEE AWHTFEDAGY MGDRIKGKSC GVYVGVEEGE YAHLTGDTDY
3661 INGTQNATLS ARIAYALDLK GPNMALTAAC SSGLVAIHQA CSALRQGDCE MALAGGVSLN
3721 ISHMSFEALT RAEMLSPNGQ CKVFDQDANG LVPGEAVAAV LLKPLSKAIE DKDHIYGCIK
3781 ASGVNYDGKT NGITAPNPFS QAELIENIYE KNEINPLDIQ YVMAHSTGSN LGDPLEVQAL
3841 TSVFSKYTKQ KQFCMISSIK PLIGHTFAAS GTVALISMLM AMKNQIIPAT HHCESENPYI
3901 PFKESPFVLC KENRSWIKKN QKPRMGTIST TGISGTNAHA VIEEYIPDDQ PSTQRHQGSP
3961 QIFVISAQND DRLQDAACRM IAYLEQNHNL SLPDVAYTLQ VGRKAMEARL AIVANNQEQL
4021 VRKLKEYVEA MKNGGVSGQQ RSLYTGYTEG ILEEQDEAVL QALAKERNLE NIAECWVKGY
4081 QIPWELLHDG DDVRMVSLPG YPFARERYWI SSGTQQSEAV KQHSQDMKTE IDEPNGKTHI
4141 QKIIVQFLAR ELGISEDRIN FKRNFLDYGM DSILGRKLMR HIEKTTQLKM AGREILECQT
4201 VQALSDHLAL KAEKQNHSAA AHHIKGTYTD EQIIGLMQEV ALGKLDFKSV QNIIEGSKSY
4261 ES
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