LOCUS X67858 5364 bp DNA linear HUM 16-OCT-1992
DEFINITION H.sapiens DNA for IG kappa JC region.
ACCESSION X67858
VERSION X67858.1
KEYWORDS Ig kappa light chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5364)
AUTHORS Garrard W.T.
JOURNAL Submitted (23-JUL-1992) to the INSDC. W.T. Garrard, UT Southwestern
Medical Centre, Department of Biochemistry, 5323 Harry Hines Blvd.,
Dallas TX 75235, USA
REFERENCE 2 (bases 1 to 5364)
AUTHORS Whitehurst C., Henney H.R., Max E.E., Schroeder H.W., Stuber F.,
Siminovitch K., Garrard W.T.
TITLE Nucleotide sequence of the intron of the germline human kappa
immunoglobulin gene connecting the J and C regions reveals a matrix
association region (MAR) next to the enhancer
JOURNAL Nucleic Acids Res. 20(18), 4929-4930(1992).
PUBMED 1408808
FEATURES Location/Qualifiers
source 1..5364
/organism="Homo sapiens"
/mol_type="genomic DNA"
/germline
/db_xref="taxon:9606"
misc_feature 252..290
/note="J1 region"
misc_feature 613..651
/note="J2 region"
misc_feature 917..955
/note="J3 region"
misc_feature 1252..1290
/note="J4 region"
misc_feature 1570..1608
/note="J5 region"
misc_feature 2661..3661
/note="matrix association region (MAR)"
regulatory 3742..3866
/regulatory_class="enhancer"
misc_feature 4491..4993
/note="constant region"
BASE COUNT 1623 a 1035 c 1114 g 1592 t
ORIGIN
1 ataaataata agcagtccag atgtggcaag ttgcaaagaa aggaaccatc aggccataga
61 cgtaaatata ttctcttctt ggattttagg tctcacctaa agaaaataaa cacatgctat
121 gtcagagaag cctcagggtt tccacacctg ctcgaaaagg gagttgagct tcagcagctg
181 acccaggact ctgttcccct ttggtgagaa gggtttctgt tcagcaagac aatggagagc
241 tctcactgtg gtggacgttc ggccaaggga ccaaggtgga aatcaaacgt gagtagaatt
301 taaactttgc ttcctcagtt gtctgtgtct tctgttccct gtgtctatga agtgatctat
361 aaggtgactc tgcaatcagc ctctgatatc cttcagggaa aagataaaga taagtctgta
421 gtcaaactcg agaattgatt gcacattttc tttgaagagc aagcaagatt cagtcattgg
481 gtgagaataa cttgtctaag taatagcttc agaaatgtcc tggggaacat aacatgttct
541 ggacagagcc ttggtcaatt gtcagaaagg gagtttttgt ataggaggga agttaagagg
601 aaccattgtg tgtacacttt tggccagggg accaagctgg agatcaaacg taagtacttt
661 tttccactga ttcttcactg ttgctaatta gtttactttg tgttcctttg tgtggatttt
721 cattagtcgg atgccaggga tctaacaaac ttcattccca ggttaggtac agaggagggg
781 aaattgttcc acaggacgct agcttgtggc taatttttaa gatttctaaa tcaaaataac
841 ttcattgggg gaaagaggct tgctgagctt tcagggaggt ttttgtaaag ggaaaagtta
901 agacgaatca ctgtgattca ctttcggccc tgggaccaaa gtggatatca aacgtaagta
961 catctgtctc aattattcgt gagattttag tgccattgta tcatttgtgc aagttttgtg
1021 atattttggt tgaataaacc tggtgaccca gaagtaaata gcaggacacc agaaaatgaa
1081 cttaaaaagc tgagcaaata gacgaatcat tgggtttgag aggagaatag gattcatggg
1141 ggaaatgggg aagaaatagc tagatttttc tctgaacaag cagcctatct catatgattg
1201 gcttcaagag aggtttttgt tgaggggaaa gggtgagatc cctcactgtg gctcactttc
1261 ggcggaggga ccaaggtgga gatcaaacgt aagtgcactt tcctaatgct ttttcttata
1321 aggttttaaa tttggagcgt ttttgtgttt gagatattag ctcaggtcaa ttccaaagag
1381 taccagattc tttcaaaaag tcagatgagt aagggataga aaattagttc atcttaagga
1441 acagccaagc gctagccagt taagtgaggc atctcaattg caagattttc tctgcatcgg
1501 tcaggttagt gatattaaca gcgaaaagag atttttgtta aggggaaagt aattaagtta
1561 acactgtgga tcaccttcgg ccaagggaca cgactggaga ttaaacgtaa gtaatttttc
1621 actattgtct tctgaaattt gggtctgatg gccagtattg acttttagag gcttaaatag
1681 gagtttggta aagattggta aatgagggca tttaagattt gccatgggtt gcaaaagtta
1741 aactcagctt caaaaatgga tttggagaaa aaaagattaa attgctctaa actgaatgac
1801 acaaagtaaa aaaaaaaagt gtaactaaaa aggaaccctt gtatttctaa ggagcaaaag
1861 taaatttatt tttgttcact cttgccaaat attgtattgg ttgttgctga ttatgcatga
1921 tacagaaaag tggaaaaata cattttttag tctttctccc ttttgtttga taaattattt
1981 tgtcagacaa caataaaaat caatagcacg ccctaagaaa aatcagggaa aagtgaagtg
2041 tacctatttg ctatgtagaa gaggcagctt acttgaaaat cagcagcaat gttgttttta
2101 gagtctgtaa taagtaataa actcaaaaag acacattcta taggaataag ggcttcacag
2161 atagagctca ttttttaaaa atccaatttg tacattagac taaacgtgaa attatctctt
2221 attgtaatgg tggaaaggtg gttattccca aaagctcaat ctcaaagaaa tgtgtttaaa
2281 tgaaaaaaag taaataattg cattttttaa tgaccgtggg tctgtgaaaa aaataggaaa
2341 tattttaaag agtatgttct ttcattatcc tctgttatta cttgtctaca tttttattct
2401 gccaagaagg ccgtggcacc gcgagctgta gacagagccg cggtctttct cgattgagtg
2461 gctttggtgg ccatgccacc gcgctcttgg ggcagccgcc ttgccgctat gccgtggcca
2521 ccctgtgtct gcccgattaa tgctgccgta gccagctttc ctgatgcaca gtgatacaaa
2581 taatgccact aagggaaaga gaacagaaac gtaatgggcg ctgagctggg aaaaccaggg
2641 agaagactga tttattagag atttcagaaa taaaattcac attcattatg atatctcatt
2701 agtgaaaatt tccattaggg gattgtaaat aatttaaagc tttttttttt tcagtgctat
2761 ttaattattt caatatcctc tcatcaaatg tatttaaata acaaaagctc aaccaaaaag
2821 aaagaaatat gtaattcttt cagagtaaaa atcacaccca tgacctggcc actgagggct
2881 tgatcaattc actttgaatt tggcattaaa taccattaag gtatattaac tgattttaaa
2941 ataagatata ttcgtgacca tgtttttaac tttcaaaaat gtagctgcca gtgtgtgatt
3001 ttatttcagt tgtacaaaat atctaaacct atagcaatgt gattaataaa aacttaaaca
3061 tattttccag taccttaatt ctgtgatagg aaaattttaa tctgagtatt ttaatttcat
3121 aatctctaaa atagtttaat gatttgtcat tgtgttgctg tcgtttaccc cagctgatct
3181 caaaagtgat atttaaggag attattttgg tctgcaacaa cttgatagga ctattttagg
3241 gcctttttaa agctctatta aaactaactt acaacgattc aaaactgttt taaactattt
3301 caaaatgatt ttagagcctt ttgaaaactc ttttaaacac tttttaaact ctattaaaac
3361 taataagata acttgaaata attttcatgt caaatacatt aactgtttaa tgtttaaatg
3421 ccagatgaaa aatgtaaagc tatcaagaat tcacccagat aggagtatct tcatagcatg
3481 tttttccctg cttattttcc agtgatcaca ttattttgct accatggtta ttttatacaa
3541 ttatctgaaa aaaattagtt atgaagatta aaagagaaga aaatattaaa cataagagat
3601 tcagtctttc atgttgaact gcttggttaa cagtgaagtt agttttaaaa aaaaaaaaaa
3661 ctatttctgt tatcagctga cttctcccta tctgttgact tctcccagca aaagattctt
3721 attttacatt ttaacctact gctctcccac ccaacgggtg gaatccccca gagggggatt
3781 tccaagaggc cacctggcag ttgctgaggg tcagaagtga agctagccac ttcctcttag
3841 gcaggtggcc aagattacag ttgacctctc ctggtatggc tgaaaattgc tgcatatggt
3901 tacaggcctt gaggcctttg ggagggctta gagagttgct ggaacagtca gaaggtggag
3961 gggctgacac cacccaggcg cagaggcagg gctcagggcc tgctctgcag ggaggtttta
4021 gcccagccca gccaaagtaa cccccgggag cctgttatcc cagcacagtc ctggaagagg
4081 cacaggggaa ataaaagcgg acggaggctt tccttgactc agccgctgcc tggtcttctt
4141 cagacctgtt ctgaattcta aactctgagg gggtcggatg acgtggccat tctttgccta
4201 aagcattgag tttactgcaa ggtcagaaaa gcatgcaaag ccctcagaat ggctgcaaag
4261 agctccaaca aaacaattta gaactttatt aaggaatagg gggaagctag gaagaaactc
4321 aaaacatcaa gattttaaat acgcttcttg gtctccttgc tataattatc tgggataagc
4381 atgctgtttt ctgtctgtcc ctaacatgcc ctgtgattat ccgcaaacaa cacacccaag
4441 ggcagaactt tgttacttaa acaccatcct gtttgcttct ttcctcagga actgtggctg
4501 caccatctgt cttcatcttc ccgccatctg atgagcagtt gaaatctgga actgcctctg
4561 ttgtgtgcct gctgaataac ttctatccca gagaggccaa agtacagtgg aaggtggata
4621 acgccctcca atcgggtaac tcccaggaga gtgtcacaga gcaggacagc aaggacagca
4681 cctacagcct cagcagcacc ctgacgctga gcaaagcaga ctacgagaaa cacaaagtct
4741 acgcctgcga agtcacccat cagggcctga gctcgcccgt cacaaagagc ttcaacaggg
4801 gagagtgtta gagggagaag tgcccccacc tgctcctcag ttccagcctg accccctccc
4861 atcctttggc ctctgaccct ttttccacag gggacctacc cctattgcgg tcctccagct
4921 catctttcac ctcacccccc tcctcctcct tggctttaat tatgctaatg ttggaggaga
4981 atgaataaat aaagtgaatc tttgcacctg tggtttctct ctttcctcaa tttaataatt
5041 attatctgtt gtttaccaac tactcaattt ctcttataag ggactaaata tgtagtcatc
5101 ctaaggcgca taaccattta taaaaatcat ccttcattct attttaccct atcatcctct
5161 gcaagacagt cctccctcaa acccacaagc cttctgtcct cacagtcccc tgggccgtgg
5221 taggagagac ttgcttcctt gttttcccct cctcagcaag ccctcatagt cctttttaag
5281 ggtgacaggt cttacggtca tatatccttt gattcaattc cctgggaatc aaccaaggca
5341 aatttttcaa aagaagaaac ctgc
//