LOCUS X63370 1528 bp DNA linear HUM 17-NOV-1995
DEFINITION H.sapiens gene for immunoglobulin kappa light chain variable region
'A30'.
ACCESSION X63370 S37650
VERSION X63370.1
KEYWORDS Ig kappa light chain; immunoglobulin light chain variable region;
J-kappa 1 gene; J-kappa 2 gene; J-kappa 3 gene; signal joint.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1528)
AUTHORS Huber C.F.M.
JOURNAL Submitted (27-NOV-1991) to the INSDC. C.F.M. Huber, Inst f Physiol
Chemie, Uni Muenchen, Schillerstrasse 44, D-8000 Muenchen 2, FRG
REFERENCE 2 (bases 1 to 1528)
AUTHORS Huber C., Klobeck H.G., Zachau H.G.
TITLE Ongoing V kappa-J kappa recombination after formation of a
productive V kappa-J kappa coding joint
JOURNAL Eur. J. Immunol. 22(6), 1561-1565(1992).
PUBMED 1601042
COMMENT Aberrant rearrangement to J-kappa 1
FEATURES Location/Qualifiers
source 1..1528
/organism="Homo sapiens"
/chromosome="2"
/map="p12 banding"
/isolate="JI"
/mol_type="genomic DNA"
/clone="JI1, JI2"
/cell_line="JI"
/db_xref="taxon:9606"
V_segment join(<1..18,144..438)
/gene="immunoglobulin kappa light chain variable region
A30"
J_segment 439..477
/gene="J-kappa 1"
J_segment 800..842
/gene="J-kappa 2"
J_segment 1104..1142
/gene="J-kappa 3"
misc_feature 1437..1438
/note="signal joint"
misc_feature 1438..>1528
/note="3' flank of B3"
BASE COUNT 420 a 303 c 369 g 436 t
ORIGIN
1 tgctgctctg gttcccaggt aaggatggag aacactagca gtttactcag cccagagtgc
61 tcagtactgc tttactgttc agggaaattc tcttacaaca tgattaattg tgtggacatt
121 tgtttttatg tttccaatct caggtgccag gtgtgacatc cagatgaccc agtctccatc
181 ctccctgtct gcatctgtaa gacagagtca ccatcacttg ccgggcaagt cagggcatta
241 gaaatgattt aggctggtat cagcagaaac cagggaaagc ccctaagcgc ctgatctatg
301 ctgcatccag tttgcaaagt ggggtcccat caaggttcag cggcagtgga tctgggacag
361 aattcactct cacaatcagc agcctgcagc ctgaagattt tgcaacttat tactgtctac
421 agcataatag ttaccctcgg gacgttcggc caagggacca aggtggaaat caaacgtgag
481 tagaatttaa actttgcttc ctcagttgtc tgtgtcttct gttccctgtg tctatgaagt
541 gatctataag gtgactctgc aatcagcctc tgatatcctt cagggaaaag ataaagataa
601 gtctgtagtc aaactcgaga attgattgca cattttcttt gaagagcaag caagattcag
661 tcattgggtg agaataactt gtctaagtaa tagcttcaga aatgtcctgg ggaacataac
721 atgttctgga cagagccttg gtcaattgtc agaaagggag tttttgtata ggagggaagt
781 taagaggaac cattgtgtgt acacttttgg ccaggggacc aagctggaga tcaaacgtaa
841 gtactttttt ccactgattc ttcactgttg ctaattagtt tactttgtgt tcctttgtgt
901 ggattttcat tagtcggatg ccagggatct aacaaacttc attcccaggt taggtacaga
961 ggaggggaaa ttgttccaca ggacgctagc ttgtggctaa tttttaagat ttctaaatca
1021 aaataacttc attgggggaa agaggcttgc tgagctttca gggaggtttt tgtaaaggga
1081 aaagttaaga cgaatcactg tgattcactt tcggccctgg gaccaaagtg gatatcaaac
1141 gtaagtacat ctgtctcaat tattcgtgag attttagtgc cattgtatca tttgtgcaag
1201 ttttgtgata ttttggttga ataaacctgg tgacccagaa gtaaatagca ggacaccaga
1261 aaatgaactt aaaaagctga gcaaatagac gaatcattgg gtttgagagg agaataggat
1321 tcatggggga aatggggaag aaatagctag atttttctct gaacaagcag cctatctcat
1381 atgattggct ccaagagagg tttttgttga ggggaaaggg tgagatccct cactgtgcac
1441 agtgcttcag cctcgaacac aaacctcctc cccatacgct gggccagtag gtctttgctg
1501 cagcagctgc ttcctctgca cacagccc
//